Results 81 to 90 of about 21,043 (239)

Genetic Variation in NFKB1 and NFKBIA and Susceptibility to Coronary Artery Disease in a Chinese Uygur Population. [PDF]

PLoS ONE, 2015
Coronary artery disease (CAD) is the most common chronic inflammatory disease worldwide. NF-κB, a central regulator of inflammation, is involved in various inflammatory diseases.
Hong-Mei Lai, Xiao-Mei Li, Yi-Ning Yang, Yi-Tong Ma, Rui Xu, Shuo Pan, Hui Zhai, Fen Liu, Bang-Dang Chen, Qian Zhao   +9 more
doaj   +1 more source

Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells [PDF]

, 2013
Activation of PKR (double-stranded-RNA-dependent protein kinase) by DNA plasmids decreases translation, and limits the amount of recombinant protein produced by transiently transfected HEK (human embryonic kidney)-293 cells.
Apostolaki, Baldi, Beinke, Beinke, Beinke, Beinke, Beinke, Belich, Bouwmeester, Ciechanover, Cohen, Coope, Costa, Dauber, Dumitru, Durocher, Elke MÜHLBERGER, Feng, Gantke, Geisse, George, Gray, Jia, Jia, Julia Janzen, Kabouridis, Kaufman, Lang, Liu, Nicholas A. Morrice, Papoutsopoulou, Pomerantz, Robinson, Roget, Sabrina Boussouf, Salmeron, Salmeron, Savinova, Schlaeger, Schumann, Steven Howell, Steven C. Ley, Thorsten Gantke, Waterfield, Waterfield, Wu, Yang, Zhao   +47 more
core   +1 more source

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

Advanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang, Hongjiang Li, Liji You, Shuhui Wang, Jinglei Bie, Ziyang Su, Lanying Shi, You‐Qiang Su   +7 more
wiley   +1 more source

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

Advanced Science, EarlyView.
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain, Yao Gao, Sharmeen Islam, Li‐Wei Chen, Xinrui Li, Zhongyun Kou, Nathan C Law, Jeanene Marie de Avila, Mei‐Jun Zhu, Min Du   +9 more
wiley   +1 more source

miRNAs and NFKB1 and TRAF6 target genes: The initial functional study in CD14+ monocytes in rheumatoid arthritis patients [PDF]

Genetics and Molecular Biology
We predicted miRNAs with regulatory impact on NFKB1 and TRAF6 gene expression and selected the miR-194-5p, miR-124-3p, miR-9-5p, and miR-340-5p and their target genes for expression analyses on CD14+ monocytes from rheumatoid arthritis (RA) patients and ...
Isaura Isabelle Fonseca Gomes da Silva, Denise de Queiroga Nascimento, Alexandre Domingues Barbosa, Fabricio Oliveira Souto, Maria de Mascena Diniz Maia, Sergio Crovella, Paulo Roberto Eleuterio de Souza, Paula Sandrin-Garcia   +7 more
doaj   +1 more source

Interaction between obesity and the NFKB1 - 94ins/delATTG promoter polymorphism in relation to incident acute coronary syndrome: a follow up study in three independent cohorts. [PDF]

PLoS ONE, 2013
The NF-κB transcription factor family regulates several genes encoding pro-inflammatory and anti-inflammatory proteins in adipose tissues and in atherosclerotic plaques. The deletion variant allele of the NFKB1 - 94ins/delATTG promoter polymorphism leads
Jakob Gerhard Stegger, Erik Berg Schmidt, Tina Landsvig Berentzen, Anne Tjønneland, Ulla Vogel, Eric Rimm, Thorkild I A Sørensen, Kim Overvad, Majken K Jensen   +8 more
doaj   +1 more source

Evolving clinical profile of HLA-DRB1, MMP1 and NF-Κb gene in rheumatoid factor positive Caucasian population [PDF]

, 2011
Rheumatoid arthritis (RA), a systemic autoimmune condition, causes joint damage and sometimes extra-articular lesions (cutaneous vasculitis, neuropathy, Felty’s syndrome, pericarditis, intersticial lung disease) that may be life threatening.
Anupama Sharma, Ajay kumar Singh, Sanjeev kumar Singh, Neelima Singh, Varsha Gupta Int J Cur Sci Res.
core  

Insertion/deletion polymorphism in promoter of NFKB1 influences

, 2009
Objective: This study investigated whether the insertionpolymorphism in the promoter of NFĸB1 is associated with the risk of bleeding after tonsillectomy. As Adamzik and coworkers could recently show, the nuclear factor ĸB which plays a critical role in host defense and in chronic inflammatory[for full text, please go to the a.m. URL]
Arweiler-Harbeck, D, Öztürk, E, Bankfalvi, A, Riemann, K, Schmid, KW, Siffert, J, Lang, S, Peters, J, Adamzik, M   +8 more
openaire   +2 more sources

Nfkb1 inhibits LPS-induced IFN-β and IL-12 p40 production in macrophages by distinct mechanisms. [PDF]

PLoS ONE, 2012
Nfkb1-deficient murine macrophages express higher levels of IFN-β and IL-12 p40 following LPS stimulation than control macrophages, but the molecular basis for this phenomenon has not been completely defined. Nfkb1 encodes several gene products including
Xixing Zhao, Erik J Ross, Yanyan Wang, Bruce H Horwitz   +3 more
doaj   +1 more source

New Synthetic Endocannabinoid as Anti-Inflammaging Cosmetic Active: an In Vitro Study on a Reconstructed Skin Model [PDF]

, 2019
Endocannabinoids have been recently appointed as interesting cosmetic actives in regulating inflammaging, a state of chronic low-grade inflammation, known for being involved in many senescence\u2019s manifestations, included skin aging.
Caviola, E, Galizia, G and Baratto G, Meloni, M, Semenzato, A   +3 more
core