Early NGF-TrkA-CGRP signaling-related changes in dorsal root ganglia are associated with mechanical hypersensitivity in a zymosan A-induced SKG model prior to overt arthritis. [PDF]
Neurobiol PainKawata Y, Funakoshi H.
europepmc +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Electroacupuncture enhances anti-tumor immunity in TNBC by reducing NE release and blocking α2-AR-mediated NGF/Hippo signaling. [PDF]
Chin MedLi FF +8 more
europepmc +1 more source
NGF rapidly increases membrane expression of TRPV1 heat‐gated ion channels
EMBO Journal, 2005 Xuming Zhang +2 more
semanticscholar +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Serum Levels of IFN-γ and NGF as Potential Biomarkers of Depressive Disorders. [PDF]
Acta NeuropsychiatrYi L, Liu C, Lin W, Duan N.
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley +1 more source
From the Perspective of the Peripheral Sensory Nervous System: The Role of Vitamin D in Neurogenic Inflammatory Skin Disorders. [PDF]
Acta Physiol (Oxf)Commaroto SA, Granstein RD.
europepmc +1 more source
Role of NGF in breast cancer angiogenesis
, 2009 Notre laboratoire a montré précédemment que le facteur NGF est produit par les cellules de cancer du sein et non par les cellules épithéliales mammaires normales.
Romon, Rodrigue
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