Results 151 to 160 of about 137,103 (391)

Ultrahigh Stiffness and Energy Absorption Properties of Isotropic Metallic Closed Cell Microlattices

open access: yesSmall, EarlyView.
True closed cell microlattices without holes are fabricated for the first time using a novel Laser Sheet Fusion additive manufacturing technique. These microlattices exhibited isotropy in stiffness and surprisingly, strength and plasticity as well, despite orientation‐dependent failure mechanisms. Furthermore, material work hardening is shown to be key
Dominic Kang Jueh Lim, Chang Quan Lai
wiley   +1 more source

Tapinarof as a Therapeutic Aryl Hydrocarbon Receptor‐Modulating Agent in the Treatment of Atopic Dermatitis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji   +7 more
wiley   +1 more source

Does Decreasing the Generosity of Payments to Single Parents Have Employment and Earnings Effects? Evidence from Australian Administrative Data*

open access: yesEconomic Record, EarlyView.
We examine the impact of two changes to Australia's Parenting Payment Single (PPS) program, a welfare payment for low‐income single mothers. One change lowered the age of the youngest child cut off for program eligibility, forcing new welfare entrants onto the less generous Newstart (unemployment) payment.
Kristen Sobeck, Robert Breunig
wiley   +1 more source

Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses

open access: yesAllergy, EarlyView.
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong   +5 more
wiley   +1 more source

Levels of BDNF and NGF in Adolescent Rat Hippocampus Neonatally Exposed to Methamphetamine Along With Environmental Alterations

open access: gold, 2023
Barbora Čechová   +4 more
openalex   +1 more source

NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
R. Tomlinson   +6 more
semanticscholar   +1 more source

A critical appraisal of the safety of bedinvetmab (Beransa), a canine antinerve growth factor monoclonal antibody

open access: yesAustralian Veterinary Journal, EarlyView.
Clinical scenario Canine osteoarthritis (OA) is a degenerative joint disease and is one of the most common chronic conditions in dogs and other species. The management of OA remains a longstanding focus in veterinary medicine. Traditionally, nonsteroidal anti‐inflammatory drugs (NSAIDs) have been the first‐line treatment option for canine OA. Recently,
X Yang, P Macarthur
wiley   +1 more source

MRD‐negative conversion with daratumumab monotherapy in newly diagnosed multiple myeloma patients in ≥VGPR/MRD‐positive after first‐line therapy: Final analysis of the open‐label, single‐arm multicentric phase 2 trial DART4MM

open access: yesBritish Journal of Haematology, EarlyView.
In newly diagnosed multiple myeloma patients in ≥Very Good Partial Remission (VGPR) after a first‐line therapy daratumumab as consolidation/maintenance improved long‐term minimal residual disease negativity. Summary Daratumumab is approved for front‐line and relapsed myeloma therapy.
Alessandro Gozzetti   +24 more
wiley   +1 more source

Nerve growth factor – its role in asthma and allergic reactions

open access: yesZdravniški Vestnik, 2005
Background: Nerve growth factor (NGF) plays an important role in the growth, differentiation and survival of peripheral and central neurons. Beside neurotrophic activity, NGF exerts several effects on the cells of immune system.
Mateja Štempelj, Ilonka Ferjan
doaj  

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