Results 151 to 160 of about 137,103 (391)
Ultrahigh Stiffness and Energy Absorption Properties of Isotropic Metallic Closed Cell Microlattices
True closed cell microlattices without holes are fabricated for the first time using a novel Laser Sheet Fusion additive manufacturing technique. These microlattices exhibited isotropy in stiffness and surprisingly, strength and plasticity as well, despite orientation‐dependent failure mechanisms. Furthermore, material work hardening is shown to be key
Dominic Kang Jueh Lim, Chang Quan Lai
wiley +1 more source
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji +7 more
wiley +1 more source
We examine the impact of two changes to Australia's Parenting Payment Single (PPS) program, a welfare payment for low‐income single mothers. One change lowered the age of the youngest child cut off for program eligibility, forcing new welfare entrants onto the less generous Newstart (unemployment) payment.
Kristen Sobeck, Robert Breunig
wiley +1 more source
Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong +5 more
wiley +1 more source
NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice
R. Tomlinson +6 more
semanticscholar +1 more source
Clinical scenario Canine osteoarthritis (OA) is a degenerative joint disease and is one of the most common chronic conditions in dogs and other species. The management of OA remains a longstanding focus in veterinary medicine. Traditionally, nonsteroidal anti‐inflammatory drugs (NSAIDs) have been the first‐line treatment option for canine OA. Recently,
X Yang, P Macarthur
wiley +1 more source
In newly diagnosed multiple myeloma patients in ≥Very Good Partial Remission (VGPR) after a first‐line therapy daratumumab as consolidation/maintenance improved long‐term minimal residual disease negativity. Summary Daratumumab is approved for front‐line and relapsed myeloma therapy.
Alessandro Gozzetti +24 more
wiley +1 more source
Nerve growth factor – its role in asthma and allergic reactions
Background: Nerve growth factor (NGF) plays an important role in the growth, differentiation and survival of peripheral and central neurons. Beside neurotrophic activity, NGF exerts several effects on the cells of immune system.
Mateja Štempelj, Ilonka Ferjan
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