Results 141 to 150 of about 137,103 (391)

Stem cell–mediated neuroplasticity and psychological recovery in cancer survivors: Mechanisms, evidence, and translational challenges

open access: yesPrecision Medical Sciences, EarlyView.
Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley   +1 more source

Cordycepin improved neuronal synaptic plasticity through CREB-induced NGF upregulation driven by MG-M2 polarization: a microglia-neuron symphony in AD

open access: gold, 2022
Linchi Jiao   +13 more
openalex   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

open access: yesPhytotherapy Research, EarlyView.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta   +7 more
wiley   +1 more source

Comparison of Voluntary, Forced, and Water-Resistance Exercise on Hippocampal BDNF and NGF Expression in a Mouse Model of Alzheimer\'s Disease [PDF]

open access: yesElderly Health Journal
Introduction: Alzheimer’s disease is a progressive brain disorder that causes impairments in memory, thinking, and behavior. The aim of this study was to compare the effects of eight weeks of voluntary, forced, and resistance training in water on the ...
Younes baziyar   +4 more
doaj  

Dermal macrophages set pain sensitivity by modulating tissue NGF levels through SNX25–Nrf2 signaling [PDF]

open access: green, 2021
Tatsuhide Tanaka   +10 more
openalex   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

open access: yesPhytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández   +5 more
wiley   +1 more source

In Vitro Reconstruction of Axonal Heat Sensing with a Photothermal Nerve‐on‐a‐Chip

open access: yesSmall, EarlyView.
A photothermal nerve‐on‐a‐chip platform is presented that enables precise, localized heating of sensory axons with simultaneous electrical recording. The system reveals millisecond‐scale dynamics of heat‐evoked neural activity and provides a new approach to study how temperature‐dependent ion channel behavior is translated into axonal firing.
Koji Sakai   +6 more
wiley   +1 more source

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