Results 141 to 150 of about 94,176 (342)
Nerve growth factor (NGF) in the central nervous system [PDF]
, 1990 Bandtlow, Christine +9 more
core +1 more source
Imidazoline receptor antisera-selected protein: a unique modulator of neuronal differentiation. [PDF]
, 2008 The imidazoline I1 receptor (I1-R) is a novel receptor found primarily in the brain and nervous tissue where it modulates neurotransmission. It is named for its high affinity for compounds with an imidazoline structure such as the anti-hypertensive drugs,
Dehle, Francis Christian
core
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study aimed to investigate associations of plasma and synovial fluid vascular endothelial growth factor A (VEGF‐A) and neuropilin‐1 (NRP1) levels with radiographic severity, pain sensitization‐related features, and disease burden in knee osteoarthritis (KOA). Plasma VEGF‐A and NRP1 were measured by sandwich ELISA in 120 patients with KOA (
Cheng‐Ju Tan
wiley +1 more source
Delivery of NGF to the Brain: Intranasal versus Ocular Administration in Anti-NGF Transgenic Mice
, 2009 Nerve growth factor (NGF) has a great potential for the treatment of Alzheimer's disease. However, the therapeutic administration of NGF represents a significant challenge, due to the difficulty to deliver relevant doses to the brain, in a safe and non ...
Gabriele Ugolini +15 more
core +1 more source
Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
Med Research, EarlyView.An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu +9 more
wiley +1 more source
The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors
Medicinal Research Reviews, EarlyView.ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti +6 more
wiley +1 more source
NGF and NGF-receptor expression of cultured immortalized human corneal endothelial cells
, 2010 Purpose: Several growth factors, including nerve growth factor (NGF) and vascular endothelial growth factor (VEGF), play an important role in the homeostasis of the ocular surface.
Lambiase A +3 more
core +1 more source
Coexisting ant species differ in ability to meet their intrinsic nutritional needs
Oikos, EarlyView.Coexisting species are often assumed to reduce competition by foraging for foods that differ in nutrient composition, but few studies test whether field nutritional differences correspond to intrinsic differences in macronutrient selectivity. We compared field estimates of worker trophic position (tissue isotopes: δ15N) and worker tissue stoichiometry (
Hannah L. Riskas +4 more
wiley +1 more source
Precision Medical Sciences, EarlyView.Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley +1 more source