Abstract Atrial fibrillation (AF), the most common clinical arrhythmia, is driven by inflammatory activation and oxidative stress, though precise molecular links remain unclear. This study identifies the P2X7 receptor as a key upstream regulator orchestrating proarrhythmic atrial remodeling through reactive oxygen species (ROS)‐mediated mitogen ...
Lingnan Zhang, Yeran Zhu, Xinshun Gu
wiley +1 more source
Change of guards: ELAVL proteins switch miRNA export responsibility to regulate differentiation of PC12 cells. [PDF]
Ray S, Bhattacharyya SN, Mukherjee K.
europepmc +1 more source
Changji’an formula alleviates visceral hypersensitivity of a post-inflammatory IBS-D mouse model via NGF/TrkA signaling pathway [PDF]
Wei Ke +9 more
openalex +1 more source
Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun +7 more
wiley +1 more source
Effect of specific mode electroacupuncture stimulation combined with NGF on dysphagia after ischemic stroke: study protocol for a pilot randomized controlled trial. [PDF]
Yu X +9 more
europepmc +1 more source
IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life.
D. Molliver +7 more
semanticscholar +1 more source
RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling
Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro +4 more
wiley +1 more source
TGF-β1 Promotes the Recovery of Dorsal Root Ganglion Neurons from Cisplatin-Induced Injury Through Smad4-Dependent Mechanism. [PDF]
Wu P, Wei Y, Chen X, Mo Q, Zhuo M.
europepmc +1 more source
Nerve Bundle Density and Expression of NGF and IL-1β Are Intra-Individually Heterogenous in Subtypes of Endometriosis [PDF]
Mahfuza Sreya +6 more
openalex +1 more source

