Results 11 to 20 of about 380,610 (181)

Inference of Markovian Properties of Molecular Sequences from NGS Data and Applications to Comparative Genomics [PDF]

open access: yes, 2015
Next Generation Sequencing (NGS) technologies generate large amounts of short read data for many different organisms. The fact that NGS reads are generally short makes it challenging to assemble the reads and reconstruct the original genome sequence. For
Cannon, Charles H.   +5 more
core   +1 more source

Design e Antropometria: Diferenciação Estratégica

open access: yesProjetica, 2011
A gestão de design, dentre suas diferentes atribuições, procura e promove informações estratégicas para o processo de design. Tais informações podem, por exemplo, focar na diferenciação dos produtos.
Rodrigo Petry Schoenardie   +2 more
doaj   +1 more source

Opportunities and achievements of using massive parallel sequencing in the diagnosis of neurodevelopmental diseases

open access: yesЭпилепсия и пароксизмальные состояния, 2023
The contribution of genetic factors to development of neurological diseases has long been recognized, and the majority of the advances coupled to using molecular genetic technologies resulted in identifying genes associated with the pathology of ...
T. V. Kozhanova
doaj   +1 more source

SEED: efficient clustering of next-generation sequences. [PDF]

open access: yes, 2011
MotivationSimilarity clustering of next-generation sequences (NGS) is an important computational problem to study the population sizes of DNA/RNA molecules and to reduce the redundancies in NGS data.
Bao, Ergude   +3 more
core   +2 more sources

In vitro analysis of site specific nuclease selectivity by NGS

open access: yesAIMS Bioengineering, 2021
Nucleases currently used in genome engineering induce hydrolysis of DNA phosphate backbone in a sequence-specific manner. The RNA guided nucleases describe today are recognizing a sequence with two distinct molecular interactions: first, like a ...
Vincent Brondani
doaj   +1 more source

The influence of natural pulmonary surfactant on the efficacy of siRNA-loaded dextran nanogels [PDF]

open access: yes, 2013
Aim: Topical administration of siRNA nanocarriers is a promising approach in the treatment of pulmonary disorders. Pulmonary surfactant, covering the entire alveolar surface of mammalian lungs, will be one of the first interfaces that siRNA nanocarriers ...
Braeckmans, Kevin   +4 more
core   +1 more source

Tearing down the walls: FDA approves next generation sequencing (NGS) assays for actionable cancer genomic aberrations

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
The United States Food and Drug Administration (FDA) recently approved the clinical use of two comprehensive ‘mid-size’ Next Generation Sequencing (NGS) panels calling actionable genomic aberrations in cancer.
Matteo Allegretti   +7 more
doaj   +1 more source

SCHOOL: Software for Clinical Health in Oncology for Omics Laboratories

open access: yesJournal of Pathology Informatics, 2022
Bioinformatics analysis is a key element in the development of in-house next-generation sequencing assays for tumor genetic profiling that can include both tumor DNA and RNA with comparisons to matched-normal DNA in select cases.
Chelsea K Raulerson   +6 more
doaj   +1 more source

A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing [PDF]

open access: yes, 2010
Transcriptomics (at the level of single cells, tissues and/or whole organisms) underpins many fields of biomedical science, from understanding the basic cellular function in model organisms, to the elucidation of the biological events that govern the ...
Aaron R. Jex   +95 more
core   +11 more sources

Analysis of Small RNAs of Barley Genotypes Associated with Resistance to Barley Yellow Dwarf Virus

open access: yesPlants, 2020
Barley yellow dwarf virus (BYDV) causes an often-devastating disease of cereals that is most effectively controlled by using plant genotypes that are resistant or tolerant to the virus. New barley lines Vir8:3 and Vir13:8, with pyramided resistance genes
Jana Jarošová   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy