Results 41 to 50 of about 175,969 (264)

PANITIKAN NG MAUBAN SA PAGTUTURO NG KOMUNIKASYON AT PAGPAPAYAMAN NG TALASALITAAN

open access: yes, 2021
Ang pag-aaral na ito ay isinagawa upang malaman ang pananaw sa paggamit ng panitikan ng Mauban sa pagtuturo ng komunikasyon at pagpapayaman ng talasalitaan ng mga mag-aaral na may kabuuang bilang na animnapung tagasagot mula sa unang taon ng Pambayang Kolehiyo ng Mauban na binubuo ng tatlong pangkat.
LATORRE, JONALYN M., CARADA, IMELDA G.
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Clinical reassessment of post-laboratory variant call format (VCF) files

open access: yesJournal of Biochemical and Clinical Genetics, 2018
Background: Next-generation sequencing has been leading the genetic study of human disease for the past 10 years, generating a huge amount of sequence variant data, which are stored in variant call format (VCF) files. The aim of the study was to reassess
Lamia Alsubaie   +3 more
doaj   +1 more source

Comparative Transcriptome Analysis of Two Cucumber Cultivars with Different Sensitivity to Cucumber Mosaic Virus Infection

open access: yesPathogens, 2020
Cucumber mosaic virus (CMV), with extremely broad host range including both monocots and dicots around the world, belongs to most important viral crop threats.
Zdeno Šubr   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

LAWAK NG PAGGAMIT NG MGA GURO NG MELC SA PAGLINANG NG TATLONG DOMEYN NG PAGKATUTO

open access: yes
Ang pag-aaral na ito ay naglalayong suriin ang lawak ng paggamit ng mga guro ng MELCs (Most Essential Learning Competencies) sa paglinang ng tatlong domeyn ng pagkatuto sa Filipino mula sa pananaw ng mga mag-aaral. Isinagawa ito sa Metro Dumaguete College at ang mga respondente ay binubuo ng 112 mga mag-aaral mula sa Grade 11 at Grade 12, kasama ang ...
Repollo, Jeckson B.   +1 more
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Artificial intelligence used in genome analysis studies

open access: yesThe EuroBiotech Journal, 2018
Next Generation Sequencing (NGS) or deep sequencing technology enables parallel reading of multiple individual DNA fragments, thereby enabling the identification of millions of base pairs in several hours.
D’Agaro Edo
doaj   +1 more source

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