Results 51 to 60 of about 229,275 (305)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Identification of MSRA gene in the range of 8:8746888–9177947 adjacent to ARS-BFGL-NGS-26667 SNP.
, 2023 Identification of MSRA gene in the range of 8:8746888–9177947 adjacent to ARS-BFGL-NGS-26667 SNP.
Anna Maria Johansson (8828051) +5 more
core +1 more source
Advancements and Applications of STR Kits in Forensic DNA Profiling: A Comprehensive Review
Baghdad Journal of Biochemistry and Applied Biological SciencesShort tandem repeat (STR) analysis is a crucial technique in forensic science, providing high-resolution DNA profiling for criminal investigations, paternity tests, and identification of missing persons.
Omar A Mahmoud +7 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
ngs-workshop_SYD-2015-05: Sydney May 2015 NGS Workshop
, 2015 NGS Workshop: Sydney May ...
Xi Li +4 more
core +1 more source
, 2023 Identification of MEGF11 gene in the range of 10:12763643–13171387 adjacent to ARS-BFGL-NGS-71414 SNP.
Anna Maria Johansson (8828051) +5 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Clinical reassessment of post-laboratory variant call format (VCF) files
Journal of Biochemical and Clinical Genetics, 2018 Background: Next-generation sequencing has been leading the genetic study of human disease for the past 10 years, generating a huge amount of sequence variant data, which are stored in variant call format (VCF) files. The aim of the study was to reassess
Lamia Alsubaie +3 more
doaj +1 more source
Pathogens, 2020 Cucumber mosaic virus (CMV), with extremely broad host range including both monocots and dicots around the world, belongs to most important viral crop threats.
Zdeno Šubr +5 more
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source