Results 281 to 290 of about 87,888 (339)
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Control of brain tumor growth by reactivating myeloid cells with niacin
Science Translational Medicine, 2020By rejuvenating the deficient activity of myeloid cells in glioblastoma, niacin improves the treatment of otherwise incurable brain tumors. An old vitamin’s new tricks Although innate immune cells are typically present inside tumors, they often have an ...
S. Sarkar +10 more
semanticscholar +1 more source
Southern Medical Journal, 1983
We report a case of severe liver injury occurring on two occasions in a patient ingesting large doses of nicotinic acid. The liver architecture was markedly distorted, with both massive and submassive lobular collapse and marked cholestasis. Complete resolution of biochemical and histologic abnormalities occurred after withdrawal of these drugs.
D J, Patterson +3 more
openaire +2 more sources
We report a case of severe liver injury occurring on two occasions in a patient ingesting large doses of nicotinic acid. The liver architecture was markedly distorted, with both massive and submassive lobular collapse and marked cholestasis. Complete resolution of biochemical and histologic abnormalities occurred after withdrawal of these drugs.
D J, Patterson +3 more
openaire +2 more sources
Nutrition and Cancer, 2003
The dietary status of niacin (vitamin B3) has the potential to influence DNA repair, genomic stability, and the immune system, eventually having an impact on cancer risk, as well as the side effects of chemotherapy in the cancer patient. In addition to its well-known redox functions in energy metabolism, niacin, in the form of NAD, participates in a ...
openaire +3 more sources
The dietary status of niacin (vitamin B3) has the potential to influence DNA repair, genomic stability, and the immune system, eventually having an impact on cancer risk, as well as the side effects of chemotherapy in the cancer patient. In addition to its well-known redox functions in energy metabolism, niacin, in the form of NAD, participates in a ...
openaire +3 more sources
The benefits of niacin in atherosclerosis
Current Atherosclerosis Reports, 2001Niacin favorably alters all major lipid subfractions at pharmacologic doses. Alone or in combination, it promotes regression of coronary artery disease, decreases coronary events, stroke, and total mortality. Major recent progress in niacin is in four areas.
S. Tavintharan, Moti L. Kashyap
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Niacin therapy in atherosclerosis
Current Opinion in Lipidology, 2004Well designed, randomized, placebo-controlled studies show that niacin prevents cardiovascular disease and death. Unfortunately, early studies and anecdotal evidence have limited its use by promoting the opinion that niacin is intolerable and contraindicated in diabetes.
Vaijinath S. Kamanna +2 more
openaire +4 more sources
Tubercle, 1965
Summary A convenient technique is described for distinguishing between Myco. tuberculosis and other mycobacteria by the biological assay of niacin produced in subculture. Results are usually obtained in eight days. The method dispenses with the need for cyanogen bromide and enables results to be obtained with dysgonic strains.
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Summary A convenient technique is described for distinguishing between Myco. tuberculosis and other mycobacteria by the biological assay of niacin produced in subculture. Results are usually obtained in eight days. The method dispenses with the need for cyanogen bromide and enables results to be obtained with dysgonic strains.
openaire +3 more sources
Adipokines and treatment with niacin
Metabolism, 2006Adipokines may serve as an important etiologic link between atherosclerosis and obesity. Because adipose tissue is one site of action of the lipid-lowering drug niacin, we investigated whether niacin treatment would affect not only lipids but also adipokines. Twenty-four patients were treated with extended-release niacin.
Ruma Makarova +4 more
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The Promise of Niacin in Neurology
Neurotherapeutics, 2023Emily C. Wuerch, G. Urgoiti, V. Yong
semanticscholar +1 more source
The American Journal of Cardiology, 2008
Nicotinic acid (niacin) has long been used for the treatment of lipid disorders and cardiovascular disease. Niacin favorably affects apolipoprotein (apo) B-containing lipoproteins (eg, very-low-density lipoprotein [VLDL], low-density lipoprotein [LDL], lipoprotein[a]) and increases apo A-I-containing lipoproteins (high-density lipoprotein [HDL ...
Moti L. Kashyap, Vaijinath S. Kamanna
openaire +3 more sources
Nicotinic acid (niacin) has long been used for the treatment of lipid disorders and cardiovascular disease. Niacin favorably affects apolipoprotein (apo) B-containing lipoproteins (eg, very-low-density lipoprotein [VLDL], low-density lipoprotein [LDL], lipoprotein[a]) and increases apo A-I-containing lipoproteins (high-density lipoprotein [HDL ...
Moti L. Kashyap, Vaijinath S. Kamanna
openaire +3 more sources
The American Journal of Cardiology, 1994
Abstract Treating hypercholesterolemia is effective both for the prevention and regression of coronary artery disease. 1–3 Lipid-lowering agents are being used more frequently and practitioners are therefore more likely to encounter the unusual side effects of these drugs.
Robert A. Phillips +3 more
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Abstract Treating hypercholesterolemia is effective both for the prevention and regression of coronary artery disease. 1–3 Lipid-lowering agents are being used more frequently and practitioners are therefore more likely to encounter the unusual side effects of these drugs.
Robert A. Phillips +3 more
openaire +3 more sources