Results 121 to 130 of about 3,289 (188)

Nicastrin haploinsufficiency alters expression of type I interferon‐stimulated genes: the relationship to familial hidradenitis suppurativa

, 2019
Li Cao, David Morales-Heil, Elisha Roberson   +2 more
openalex   +2 more sources

Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration [PDF]

, 2009
Katsuhiko Tabuchi, Guiquan Chen, Thomas C. Südhof, Jie Shen   +3 more
openalex   +1 more source

Dowling-Degos Disease with Multiple Seborrheic Keratosis: An Atypical Presentation in Two Siblings. [PDF]

Indian Dermatol Online J
Ankita, Singhal A, Bisherwal K, Sharma S, Singal A.   +4 more
europepmc   +1 more source

P4‐296: Oxidative lipid modification of nicastrin enhances amyloidgenic γ‐secretase activity in Alzheimer's disease [PDF]

, 2012
A‐Ryeong Gwon, Jong Sung Park, Thiruma V. Arumugam, Seol‐Hee Kim, Dong‐Gyu Jo   +4 more
openalex   +1 more source

The critical role of γ-secretase and its inhibitors in cancer and cancer therapeutics. [PDF]

Int J Biol Sci, 2023
Song C, Zhang J, Xu C, Gao M, Li N, Geng Q.   +5 more
europepmc   +1 more source

The curious case of a heterozygous loss-of-function <i>PSEN1</i> variant associated with early-onset Alzheimer's disease. [PDF]

Mol Neurodegener Adv
Sanjuan-Ruiz I, Serneels L, Craessaerts K, Goate A, Annaert W, Chávez-Gutiérrez L, Shi Y, Sheikh-Bahaei N, Jen JC, Ramos EM, Campan M, Ward PM, Magaki S, Bartlone K, Vinters HV, Dominantly Inherited Alzheimer Network, Craig DW, Ringman JM, De Strooper B.   +18 more
europepmc   +1 more source

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

, 2003
W. Taylor Kimberly, Matthew J. LaVoie, Beth L. Ostaszewski, Wenjuan Ye, Michael S. Wolfe, Dennis J. Selkoe   +5 more
openalex   +1 more source

The Transmembrane Domain Region of Nicastrin Mediates Direct Interactions with APH-1 and the γ-Secretase Complex [PDF]

, 2003
Vanessa A. Morais, Adam Crystal, Donald S. Pijak, Dan Carlin, Júlia Costa, Virginia M.‐Y. Lee, Robert W. Doms   +6 more
openalex   +1 more source

Thermal proteome profiling unveils protein targets of deoxycholic acid in living neuronal cells. [PDF]

Adv Biotechnol (Singap), 2023
Luan H, Li X, Zhang W, Luan T.
europepmc   +1 more source

Is SAPHO Syndrome Linked to PASH Syndrome and Hidradenitis Suppurativa by Nicastrin Mutation? A Case Report [PDF]

, 2018
Chengrang Li, Haoxiang Xu, Baoxi Wang
openalex   +1 more source