Results 31 to 40 of about 424,898 (313)

Riboflavin Status in Pregnancy and Its Relationship with Blood Pressure, Heart Rate and Risk of Hypertension: Findings from the OptiPREG Observational Study

open access: yesProceedings, 2023
Clinical riboflavin deficiency is common in low- and middle-income countries, whilst sub-optimal riboflavin status may be much more prevalent globally than generally recognized, including in high-income countries.
Bethany Duffy   +6 more
doaj   +1 more source

Maternal Serum Cytokine Concentrations in Healthy Pregnancy and Preeclampsia

open access: yesJournal of Pregnancy, 2021
The maternal immune response is essential for successful pregnancy, promoting immune tolerance to the fetus while maintaining innate and adaptive immunity. Uncontrolled, increased proinflammatory responses are a contributing factor to the pathogenesis of
Toni Spence   +5 more
doaj   +1 more source

Niche Occupation Limits Adaptive Radiation in Experimental Microcosms [PDF]

open access: yes, 2007
Adaptive radiations have played a key role in the evolution of biological diversity. The breadth of adaptive radiation in an invading lineage is likely to be influenced by the availability of ecological niches, which will be determined to some extent by ...
Colegrave, Nick   +12 more
core   +2 more sources

Notch in the Niche [PDF]

open access: yesCell Stem Cell, 2008
Notch signaling is essential for hematopoietic stem cell (HSC) formation during embryogenesis, and hitherto it was also thought to be required for HSC maintenance. However, in this issue of Cell Stem Cell, Maillard et al. (2008) demonstrate rather conclusively that inactivation of the Notch pathway in HSCs does not interfere with their self-renewal.
Gering, M, Patient, R
openaire   +1 more source

La niche écologique, mythe ou réalité ? [PDF]

open access: yes, 1979
The niche concept in ecology can be approached either empi rically or theoretically. The emphasis is laid in this paper on the empirical approach, and the authors make use of their per- sonnal field experience to illustrate the points discussed.
Bourlière, François, Blondel, Jacques
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Niche Revealed [PDF]

open access: yesCell Stem Cell, 2008
SummaryA trio of studies in this issue of Cell Stem Cell from Mirzadeh et al., Shen et al., and Tavazoie et al. use three-dimensional imaging techniques to reveal microanatomical details of the adult neural stem cell niche. Combined, the results also provide a framework for future functional studies.
Currle, D. Spencer   +1 more
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Investigation of the heterogeneity of cancer cells using single cell Ca2+ profiling

open access: yesCell Communication and Signaling
Background Calcium (Ca2+) is an essential second messenger that controls numerous cellular functions. Characteristics of intracellular Ca2+ oscillations define Ca2+ signatures representatives of the phenotype of a cell.
Amélie E. Bura   +11 more
doaj   +1 more source

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