Results 31 to 40 of about 252,702 (266)

Niche definition and guidance for detailed niche evaluation [PDF]

open access: yesActa Obstetricia et Gynecologica Scandinavica, 2019
With interest we read the correspondence of Bamberg et al.1 and Scioscia et al.2 about the randomized controlled trial of the first authors concerning the uterine niche after caesarean section (CS).3 They state that at the time of the trial it was not established which technique should be used in the evaluation of a caesarean scar or niche in daily ...
Jordans, Inge P.M.   +18 more
openaire   +4 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state

open access: yesJournal of Hematology & Oncology, 2021
Background Little is known about endogenous inhibitors of angiogenic growth factors. In this study, we identified a novel endogenous anti-angiogenic factor expressed in pericytes and clarified its underlying mechanism and clinical significance.
Jin-Woo Lee   +16 more
doaj   +1 more source

Isotopic niche is not equal to trophic niche

open access: yesEcology Letters, 2019
AbstractThe work of Sheppard et al. (Ecol. Lett., 21, 2018, 1395) relies on the strong assumption that isotopic niche is equal to trophic niche. Here I raise three main concerns showing that classic hypotheses built upon trophic niche cannot be directly interpreted in isotopic space.
openaire   +5 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Investigation of the heterogeneity of cancer cells using single cell Ca2+ profiling

open access: yesCell Communication and Signaling
Background Calcium (Ca2+) is an essential second messenger that controls numerous cellular functions. Characteristics of intracellular Ca2+ oscillations define Ca2+ signatures representatives of the phenotype of a cell.
Amélie E. Bura   +11 more
doaj   +1 more source

Resistin Regulates Inflammation and Insulin Resistance in Humans via the Endocannabinoid System

open access: yesResearch
Resistin plays an important role in the pathophysiology of obesity-mediated insulin resistance in mice. However, the biology of resistin in humans is quite different from that in rodents. Therefore, the association between resistin and insulin resistance
Han-Mo Yang   +11 more
doaj   +1 more source

Engineering of Eu dopant segregation in colquiriite-type fluoride single crystal scintillators

open access: yesAIP Advances, 2017
Colquiriite-type Eu-doped LiCaAlF6 and LiSrAlF6 (Eu:LiCAF and Eu:LiSAF) scintillator single crystals were grown using Al metal as a starting material to improve the Eu dopant segregation.
Yuui Yokota   +5 more
doaj   +1 more source

FILTROS EPISTEMOLÓGICOS PARA A ANÁLISE DOS DADOS – CONSTRUCTO METODOLÓGICO PARA A PESQUISA QUALITATIVA

open access: yesCompetência, 2016
O presente artigo apresenta uma síntese teórico-epistemológica resultante do constructo metodológico adotado no processo investigativo que contemplou discursos de docentes e discentes sobre práticas pedagógicas no âmbito da ...
Augusto Niche Teixeira   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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