Results 71 to 80 of about 927,461 (351)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Capturing the dynamics of response variability in the brain in ADHD

open access: yesNeuroImage: Clinical, 2015
ADHD is characterized by increased intra-individual variability in response times during the performance of cognitive tasks. However, little is known about developmental changes in intra-individual variability, and how these changes relate to cognitive ...
Janna van Belle   +5 more
doaj   +1 more source

Animating and sustaining niche social networks [PDF]

open access: yes, 2012
Within the communicative space online Social Network Sites (SNS) afford, Niche Social Networks Sites (NSNS) have emerged around particular geographic, demographic or topic-based communities to provide what broader SNS do not: specified and targeted ...
Spurgeon, Christina, Swift, Adam
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

The Nexus Between Plant and Plant Microbiome: Revelation of the Networking Strategies

open access: yesFrontiers in Microbiology, 2020
The diversity of plant-associated microbes is enormous and complex. These microbiomes are structured and form complex interconnected microbial networks that are important in plant health and ecosystem functioning.
Olubukola Oluranti Babalola   +5 more
doaj   +1 more source

Translucent windows: How uncertainty in competitive interactions impacts detection of community pattern [PDF]

open access: yes, 2018
Trait variation and similarity among coexisting species can provide a window into the mechanisms that maintain their coexistence. Recent theoretical explorations suggest that competitive interactions will lead to groups, or clusters, of species with ...
D'Andrea, Rafael   +2 more
core   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Developmental differences in higher-order resting-state networks in Autism Spectrum Disorder

open access: yesNeuroImage: Clinical, 2014
Objective: Autism Spectrum Disorder (ASD) has been associated with a complex pattern of increases and decreases in resting-state functional connectivity.
Dienke J. Bos   +7 more
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Evolution of Ecological Niche Breadth [PDF]

open access: yes, 2017
How ecological niche breadth evolves is central to adaptation and speciation and has been a topic of perennial interest. Niche breadth evolution research has occurred within environmental, ecological, evolutionary, and biogeographical contexts, and ...
Montiel, Jorge   +4 more
core   +1 more source

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