Results 141 to 150 of about 4,650 (177)

Dermal absorption of niclosamide in rats and minipigs

Biopharmaceutics & Drug Disposition, 1991
AbstractThe dermal absorption of niclosamide, a drug shown to prevent Schistosomiasis by blocking the dermal penetration of cercariae, has been examined in Sinclair minipigs and rats. Radioactivity in the urine and feces collected daily for 7 days after application of 14C‐niclosamide accounted for less than 2 per cent and 10 per cent of the labelled ...
P, Brennan, D, Johnson, S, Rider, N, Cone, M, Goldman, A, Buckpitt, H, Chung   +6 more
openaire   +2 more sources

Niclosamide: A career builder

Journal of Controlled Release
My contribution to honoring Professor Kinam Park celebrates and resonates with his scholarly career in drug delivery, his commitment to encouraging the next generation(s), and his efforts to keep us focused on clinically effective formulations. To do this I take as my example, niclosamide, a small molecule protonophore that, uniquely, can "target" all ...
openaire   +2 more sources

Indirect photodegradation of the lampricides TFM and niclosamide

Environmental Science: Processes & Impacts, 2017
This study evaluates the contribution of indirect photolysis to the environmental fate of the lampricides TFM and niclosamide.
Megan B. McConville, Stephen P. Mezyk, Christina K. Remucal   +2 more
openaire   +2 more sources

Niclosamide Treatment of Cestodiasis

The American Journal of Tropical Medicine and Hygiene, 1970
Abstract Niclosamide was given to 81 patients with tapeworm infection. Forty-seven patients received adequate follow-up, and 46 were cured; 17 of these had previously shown no improvement with quinacrine. Results indicate that niclosamide is a safe, simple, and effective agent against infection with Taenia saginata, Diphyllobothrium latum, and ...
D R, Perera, K A, Western, M G, Schultz
openaire   +2 more sources

Niclosamide Analogs for Treatment of Ovarian Cancer

International Journal of Gynecological Cancer, 2015
Niclosamide has shown activity against ovarian cancer in vitro; however, it has low bioavailability in vivo. Therefore, we investigated the cytotoxicity of niclosamide analogs in combination with carboplatin against ovarian cancer patient ascites cells and tissue slices.Tumorspheres were isolated from ascites collected from patients undergoing ovarian ...
Christen L, Walters Haygood, Rebecca C, Arend, Abhishek, Gangrade, Somsundaram, Chettiar, Nicholas, Regan, Christopher J, Hassmann, Pui-Kai, Li, Bertha, Hidalgo, John Michael, Straughn, Donald J, Buchsbaum   +9 more
openaire   +2 more sources

Niclosamide

2007
S.J. Enna, David B. Bylund
openaire   +2 more sources

Combination of niclosamide and current therapies to overcome resistance for cancer: New frontiers for an old drug

Biomedicine and Pharmacotherapy, 2022
Guiling Wang, Qifeng Wu
exaly  

Niclosamide overdose

Reactions Weekly, 2023
openaire   +1 more source

Repurposing of antiparasitic niclosamide to inhibit respiratory syncytial virus (RSV) replication

Virus Research, 2021
Prasert Auewarakul, Arunee Thitithanyanont, Ornpreya Suptawiwat   +2 more
exaly  

PHARMACEUTICAL COMPOSITIONS OF NICLOSAMIDE

2021
WILLIAMS III ROBERT O, SMYTH HUGH D C, WARNKEN ZACHARY N, JARA GONZALEZ MIGUEL ORLANDO, SEO HYO-JONG, BRUNAUGH ASHLEE D, HERPIN MATTHEW   +6 more
openaire   +2 more sources