Results 131 to 140 of about 226,714 (349)

Dual‐Emission Carbon Dot Nanozymes Mitigate Salt Stress and Enhance Photosynthesis for Crop Germination and Growth

open access: yesAdvanced Science, EarlyView.
Dual‐emission carbon dot nanozymes are synthesized via microwave method. The nanozymes enhance photosynthesis corn seedlings through spectral‐matched light conversion. Their superoxide dismutase‐mimetic activity scavenges salt stress‐induced reactive oxygen species and circumvents energy‐intensive stress responses.
Chengfu Su   +7 more
wiley   +1 more source

Redox Cascade in Chicken Skeletal Muscle: SELENOT Suppression in Selenium Deficiency Triggers Disulfidptosis via mtROS‐NADPH Dysregulation

open access: yesAdvanced Science, EarlyView.
Se deficiency downregulates SELENOT, disrupting mitochondrial function and elevating mtROS to induce glucose metabolic reprogramming, NADPH depletion, cysteine accumulation, and disulfidptosis‐mediated actin cytoskeleton collapse in chicken skeletal muscle.
Huanyi Liu   +5 more
wiley   +1 more source

Xylose Metabolism Perturbation in Yarrowia lipolytica for Efficient Succinic Acid Bioproduction from Lignocellulosic Biomass

open access: yesAdvanced Science, EarlyView.
This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong   +7 more
wiley   +1 more source

Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts. [PDF]

open access: yes, 2019
Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD+) are critical for maintaining redox homeostasis. Aging as
Brewer, Gregory J   +3 more
core  

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

open access: yesAdvanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying   +6 more
wiley   +1 more source

NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of protein-coding genes in Arabidopsis. [PDF]

open access: yes, 2019
The 5' end of a eukaryotic mRNA transcript generally has a 7-methylguanosine (m7G) cap that protects mRNA from degradation and mediates almost all other aspects of gene expression.
Cai, Zongwei   +7 more
core  

THE METHYLATION OF NICOTINAMIDE BY RAT LIVER IN VITRO

open access: hybrid, 1943
W. A. Perlzweig   +2 more
openalex   +1 more source

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