Results 151 to 160 of about 126,234 (257)

Opposing Molecular Programs in Obsessive-Compulsive Disorder and Hoarding: Transcriptome-Wide Association Studies Reveal Distinct Senescence, Complement, and Metabolic Signatures. [PDF]

Cureus
Cheung N.
europepmc   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source

Pharmacophore-Based QSAR Model of Multi Scaffolds as NAMPT Inhibitors & Scaffold Diversity Analysis. [PDF]

Molecules
Lee S, Zheng M, Kim K, Chun KH.
europepmc   +1 more source

Comparison Between Respiratory‐Triggered and Free‐Breathing Signal Acquisition Methods for Single‐Voxel Phosphorus Magnetic Resonance Spectroscopy of the Liver on a Clinical System

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The optimal protocol for clinical liver 31P‐magnetic resonance spectroscopy (MRS) remains unclear. Single‐voxel 31P‐MRS using image‐selected in vivo spectroscopy (ISIS) employs respiratory‐triggering (RT) or free‐breathing (FB) acquisition.
Kumi Ozaki, Jihun Kwon, Marc Van Cauteren, Yasutomo Katsumata, Yukichi Tanahashi, Satoshi Goshima   +5 more
wiley   +1 more source

Gut microbiome in pediatric acute pancreatitis and Crohn's disease versus irritable bowel syndrome and healthy controls

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric acute pancreatitis (AP), Crohn's disease (CD), and irritable bowel syndrome (IBS) are associated with gut dysbiosis, but differences and similarities between conditions are unknown. We hypothesized that gut microbial ecology would differ across these disorders. Methods Stool was collected from 120 subjects (AP [n = 30], CD
Neha R. Santucci, Chinenye R. Dike, Jenny Hellmann, Nicholas J. Ollberding, Qing Duan, Philip Minar, Lee A. Denson, David B. Haslam, Daniel Castillo, Maisam Abu‐El‐Haija   +9 more
wiley   +1 more source

Chromatic hyper Zagreb topological descriptors and QSPR analysis of certain skin cancer drugs. [PDF]

Front Chem
Pavithra R, Ravi Sankar J.
europepmc   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

Starving leukemia: nicotinamide phosphoribosyltransferase-dependent nicotinamide adenine dinucleotide salvage links metabolic vulnerability to therapeutic sensitivity in acute myeloid leukemia. [PDF]

Transl Cancer Res
Coelho-Silva JL, Pereira-Martins DA, Machado-Neto JA.   +2 more
europepmc   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Nicotinamide (Vitamin B3) Deficiency in Follicular Fluid of Patients With Ovarian Ageing. [PDF]

J Cell Mol Med
Bocca C, Boguenet M, Boucret L, Bouet PE, Reynier P, May-Panloup P.   +5 more
europepmc   +1 more source