Results 241 to 250 of about 222,121 (295)

Correlation between concentrations of NAMPT and NMNAT1 and the risk of upper respiratory infections in the island reef. [PDF]

World J Clin Cases
Gao GF, Yu J, Liu SY.
europepmc   +1 more source

Metabolic and redox adaptations of the corneal endothelium: From metabolic plasticity to therapeutic opportunities. [PDF]

Redox Biol
Jiang D, Hui Neo DJ, Swee-Lim Peh G, Jin P, Chen W, Mehta JS.   +5 more
europepmc   +1 more source

Nicotinamide riboside enhances liver regeneration via the MCART1/ASB3 axis in obesity-compromised rats. [PDF]

Hepatol Commun
Wang H, Li H, Liu Y, Wang X, He C, Huang J, Zhang Y, Yang Y, Ge N.   +8 more
europepmc   +1 more source

Nicotine Analogues in Oral Pouch Products and Associated Marketing Claims.

JAMA Netw Open
Ciancio JR, Kumar L, Rastogi K, Moran MB, Czaplicki L, Page MK, Jamil H, Goniewicz ML, Spindle TR.   +8 more
europepmc   +1 more source

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Nicotinamide

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Abstract Nicotinamide (vitamin B3, Niacinamide) is a water-soluble NAD⁺/NADP⁺ precursor central to epidermal energy metabolism and cutaneous homeostasis. As an ingestible nutricosmetic, a 10 mg/day dose (~66% U.S. DV) provides a functionally active yet well-tolerated intake that supports multiple skin targets.
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Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase

Bioorganic & Medicinal Chemistry Letters, 2018
Nicotinamide N-methyltransferase (NNMT) has been linked to obesity and diabetes. We have identified a novel nicotinamide (NA) analog, compound 12 that inhibited NNMT enzymatic activity and reduced the formation of 1-methyl-nicotinamide (MNA), the primary metabolite of NA by ∼80% at 2 h when dosed in mice orally at 50 mg/kg.
Sven Ruf, Mahanandeesha Siddappa Hallur, Nisha K. Anchan, Indu N. Swamy, Karthikai Raj Murugesan, Sayantani Sarkar, Lokesh Kananti Narasimhulu, V.P. Rama Kishore Putta, Shama Shaik, Devaraj Venkatapura Chandrasekar, Vishal Subhash Mane, Sanjay Venkatachalapathi Kadnur, Juluri Suresh, Ravi Kanth Bhamidipati, Manvi Singh, Raghunadha Reddy Burri, Rajendra Kristam, Herman Schreuder, Joerg Czech, Christine Rudolph, Alexander Marker, Thomas Langer, Ramesh Mullangi, Takeshi Yura, Ramachandraiah Gosu, Aimo Kannt, Saravanakumar Dhakshinamoorthy, Sridharan Rajagopal   +27 more
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Lipid Peroxidation in Nicotinamide-Deficient and Nicotinamide-Supplemented Rats

International Journal for Vitamin and Nutrition Research, 2000
Supplementation or deficiency of nicotinamide in rats may interfere with the oxidative balance, with excess leading to greater lipid peroxidation, measured by TBARS, and deficiency causing a greater consumption of antioxidants such as vitamin E and glutathione.
S S, Melo, M S, Meirelles, A A, Jordão Júnior, H, Vannucchi   +3 more
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Nicotinamide and neurocognitive function

Nutritional Neuroscience, 2014
Nicotinamide, or vitamin B3, is a precursor of nicotinamide adenine dinucleotide (NAD(+)) and is involved in a multitude of intra- and inter-cellular processes, which regulate some of the cell's metabolic, stress, and immune responses to physiological or pathological signals.
George, Rennie, Andrew C, Chen, Haryana, Dhillon, Janette, Vardy, Diona L, Damian   +4 more
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Three 2-(methysulfanyl)nicotinamides

Acta Crystallographica Section C Crystal Structure Communications, 2013
The molecular conformations of threeN-alkyl-2-(methylsulfanyl)nicotinamide derivatives, namelyN-cyclohexyl-2-(methylsulfanyl)nicotinamide, C13H18N2OS, (I),N-isopropyl-2-(methylsulfanyl)nicotinamide, C10H14N2OS, (II), in which there are two molecules in the asymmetric unit which were chosen to form a hydrogen-bonded pair, andN-(2-hydroxyethyl)-2 ...
Ligia R, Gomes, John Nicolson, Low, James L, Wardell, Alessandra C, Pinheiro, Thais C N, de Mendonça, Marcus V N, de Souza   +5 more
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Nicotinamide and the skin

Australasian Journal of Dermatology, 2014
AbstractNicotinamide, an amide form of vitamin B3, boosts cellular energy and regulates poly‐ADP‐ribose‐polymerase 1, an enzyme with important roles in DNA repair and the expression of inflammatory cytokines. Nicotinamide shows promise for the treatment of a wide range of dermatological conditions, including autoimmune blistering disorders, acne ...
Andrew C Chen, Diona L Damian
openaire   +2 more sources