Metabolic Engineering of <i>Pseudomonas putida</i> KT2440 for β-Nicotinamide Mononucleotide Biosynthesis from Glucose and Aspartate. [PDF]
MicroorganismsGao L +7 more
europepmc +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li +6 more
wiley +1 more source
New and Emerging Drug Therapy in Primary Open-Angle and Normal-Tension Glaucoma: Pharmacology, Neuroprotection and the Endpoint Problem. [PDF]
Pharmaceuticals (Basel)Mroczkowska S, Smewing L, Gherghel D.
europepmc +1 more source
Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events
Phytotherapy Research, EarlyView.An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia +1 more
wiley +1 more source
Nicotinamide Mononucleotide-Producing Probiotic Strain B12-N Attenuates Aging and Cognitive Decline in a <i>Caenorhabditis elegans</i> Model of Alzheimer's Disease: Efficacy and Underlying Mechanisms. [PDF]
FoodsWang X +10 more
europepmc +1 more source
Selective Redox Tuning Enables Potent Intracellular Reduction of Nicotinamide Cytosine Dinucleotide. [PDF]
BiomoleculesGuo X, Huang Y, Hu Y, Zhang L, Zhao ZK.
europepmc +1 more source
Therapeutic Targeting of Inflammaging and Emerging Strategies for Managing Age-Related Multimorbidity: A Narrative Review. [PDF]
Clin Interv AgingAyoub NR.
europepmc +1 more source