Results 251 to 260 of about 159,186 (304)

Investigation of the effects of nicotinamide mononucleotide on kidney damage in rats with cecal ligation and perforation sepsis model. [PDF]

Acta Cir Bras
Arslan A, Keleş DV, Parlak SN, Yakut S, Gündoğdu H, Arslantürk İ, Uzun GB, Karagöz BÖ.   +7 more
europepmc   +1 more source

NAD⁺ biology and supplementation: From mechanisms to clinical perspectives. [PDF]

Mol Biol Rep
Pandolfi S, Ghezzi C, Björklund G, Metalla M, Paone FM, Chirumbolo S.   +5 more
europepmc   +1 more source

Nicotinamide mononucleotide alleviates the streptozotocin-mediated ferroptosis of islet β-cells via the Nrf2/GPX4 pathway. [PDF]

Braz J Med Biol Res
Lu D, Huang J, Meng J, Luo J, Huang X.
europepmc   +1 more source

Correction to: Nicotinamide Riboside: A Promising Treatment for Type 1 Cardiorenal Syndrome in Myocardial Infarction-Induced Acute Kidney Injury by Upregulating Nicotinamide Phosphoribosyltransferase-Mediated Nicotinamide Dinucleotide Levels. [PDF]

J Am Heart Assoc
europepmc   +1 more source

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Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase

Bioorganic and Medicinal Chemistry Letters, 2018
Nicotinamide N-methyltransferase (NNMT) has been linked to obesity and diabetes. We have identified a novel nicotinamide (NA) analog, compound 12 that inhibited NNMT enzymatic activity and reduced the formation of 1-methyl-nicotinamide (MNA), the primary metabolite of NA by ∼80% at 2 h when dosed in mice orally at 50 mg/kg.
Takeshi Yura, Sven Ruf, Thomas Langer
exaly   +3 more sources

Simultaneous quantitation of nicotinamide riboside, nicotinamide mononucleotide and nicotinamide adenine dinucleotide in milk by a novel enzyme-coupled assay

Food Chemistry, 2017
Nicotinamide riboside, the most recently discovered form of vitamin B3, and its phosphorylated form nicotinamide mononucleotide, have been shown to be potent supplements boosting intracellular nicotinamide adenine dinucleotide (NAD) levels, thus ...
Simone Ummarino, Giuseppe Orsomando, Francesca Mazzola   +2 more
exaly   +2 more sources

Nicotinamide and the skin

Australasian Journal of Dermatology, 2014
AbstractNicotinamide, an amide form of vitamin B3, boosts cellular energy and regulates poly‐ADP‐ribose‐polymerase 1, an enzyme with important roles in DNA repair and the expression of inflammatory cytokines. Nicotinamide shows promise for the treatment of a wide range of dermatological conditions, including autoimmune blistering disorders, acne ...
Andrew C Chen, Diona L Damian
openaire   +2 more sources

Effect of Nicotinamide Administration on the Tryptophan-Nicotinamide Pathway in Humans

International Journal for Vitamin and Nutrition Research, 2007
The vitamin nicotinamide is synthesized in the liver from tryptophan, and distributed to non-hepatic tissues. Although it is generally accepted that 60 mg tryptophan is equivalent to 1 mg nicotinamide in humans, the conversion ratio of tryptophan to nicotinamide is changeable.
Tsutomu, Fukuwatari, Katsumi, Shibata
openaire   +2 more sources

Lipid Peroxidation in Nicotinamide-Deficient and Nicotinamide-Supplemented Rats

International Journal for Vitamin and Nutrition Research, 2000
Supplementation or deficiency of nicotinamide in rats may interfere with the oxidative balance, with excess leading to greater lipid peroxidation, measured by TBARS, and deficiency causing a greater consumption of antioxidants such as vitamin E and glutathione.
S S, Melo, M S, Meirelles, A A, Jordão Júnior, H, Vannucchi   +3 more
openaire   +2 more sources