Results 251 to 260 of about 132,023 (311)

Characterizing the tuberculosis and type 2 diabetes mellitus comorbidity in a South African cohort using untargeted GCxGC-TOFMS metabolomics. [PDF]

Metabolomics
Reinecke K, Kleynhans L, Ronacher K, Loots DT.   +3 more
europepmc   +1 more source

He-He-Shu-Yang formula alleviates liver fibrosis by inhibiting hepatic stellate cell activation <i>in vivo</i> and <i>in vitro</i>. [PDF]

World J Hepatol
Zeng FL, Shi MJ, Mo YS, Xiao HM, Xie YB, Chi XL.   +5 more
europepmc   +1 more source

Virological and Immunological Outcomes of Combined Therapeutic Interventions and Dendritic Cell Therapy in People With HIV. [PDF]

J Infect Dis
Ndhlovu LC, Giron LB, Galinskas J, Premeaux TA, Pang APS, Dias D, de Almeida Baptista MV, Shytaj IL, Maricato JT, Ferreira PRA, Gosuen G, Corley MJ, Friday CM, Bowler SA, Della Libera E, Sucupira MC, Hunter JR, Janini LM, Schechter M, Savarino A, Diaz RS, SPARC Working Group .   +21 more
europepmc   +1 more source

FOXO1-NMNAT3 axis dysregulation promotes doxorubicin cardiotoxicity: NAD⁺ replenishment as a redox-targeted antioxidant therapy. [PDF]

Redox Rep
Cheng F, Zhao M, Wang Q, Xiong H, Yu K, Chen C, Zhu Y, Chen Y, Li J.   +8 more
europepmc   +1 more source

Effects of nicotinamide riboside on NAD+ levels, cognition, and symptom recovery in long-COVID: a randomized controlled trial. [PDF]

EClinicalMedicine
Wu CY, Reynolds WC, Abril I, McManus AJ, Brenner C, González-Irizarry G, Gutiérrez-Martínez L, Sun O, Rosand J, Tanzi RE, Arnold SE, Guzmán-Vélez E.   +11 more
europepmc   +1 more source

The DIKW of Transcriptomics in Ecotoxicology: Extracting Information, Knowledge, and Wisdom From Big Data

Environmental Toxicology and Chemistry, EarlyView.
Jessica A. Head, Jessica D. Ewald, Niladri Basu   +2 more
wiley   +1 more source

Error in Figure 4.

JAMA Dermatol
europepmc   +1 more source

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Nicotinamide

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Abstract Nicotinamide (vitamin B3, Niacinamide) is a water-soluble NAD⁺/NADP⁺ precursor central to epidermal energy metabolism and cutaneous homeostasis. As an ingestible nutricosmetic, a 10 mg/day dose (~66% U.S. DV) provides a functionally active yet well-tolerated intake that supports multiple skin targets.
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Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase

Bioorganic & Medicinal Chemistry Letters, 2018
Nicotinamide N-methyltransferase (NNMT) has been linked to obesity and diabetes. We have identified a novel nicotinamide (NA) analog, compound 12 that inhibited NNMT enzymatic activity and reduced the formation of 1-methyl-nicotinamide (MNA), the primary metabolite of NA by ∼80% at 2 h when dosed in mice orally at 50 mg/kg.
Sven Ruf, Mahanandeesha Siddappa Hallur, Nisha K. Anchan, Indu N. Swamy, Karthikai Raj Murugesan, Sayantani Sarkar, Lokesh Kananti Narasimhulu, V.P. Rama Kishore Putta, Shama Shaik, Devaraj Venkatapura Chandrasekar, Vishal Subhash Mane, Sanjay Venkatachalapathi Kadnur, Juluri Suresh, Ravi Kanth Bhamidipati, Manvi Singh, Raghunadha Reddy Burri, Rajendra Kristam, Herman Schreuder, Joerg Czech, Christine Rudolph, Alexander Marker, Thomas Langer, Ramesh Mullangi, Takeshi Yura, Ramachandraiah Gosu, Aimo Kannt, Saravanakumar Dhakshinamoorthy, Sridharan Rajagopal   +27 more
openaire   +2 more sources