Results 91 to 100 of about 51,366 (193)

Decreased Expression of Nicotinamide Phosphoribosyltransferase in Patients with Juvenile Idiopathic Arthritis Receiving Methotrexate [PDF]

, 2013
Emily J. Fox, J. Steven Leeder, Shui Q. Ye, Mara L. Becker   +3 more
openalex   +1 more source

Deletion of Nampt in Projection Neurons of Adult Mice Leads to Motor Dysfunction, Neurodegeneration, and Death

Cell Reports, 2017
Intracellular nicotinamide phosphoribosyltransferase (iNAMPT) is the rate-limiting enzyme of the mammalian NAD+ biosynthesis salvage pathway. Using inducible and conditional knockout (cKO) mice, we show that Nampt gene deletion in adult projection ...
Xiaowan Wang, Qiao Zhang, Ruisi Bao, Nannan Zhang, Yingzhen Wang, Luis Polo-Parada, Andrew Tarim, Aidan Alemifar, Xianlin Han, Heather M. Wilkins, Russell H. Swerdlow, Xinglong Wang, Shinghua Ding   +12 more
doaj   +1 more source

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice [PDF]

, 2013
Rafaela da Silva, Rafaela da Silva, Sabine Steffens, Mathias Fabre, Inga Bauer, Irene Caffa, Mirko Magnone, Giovanna Sociali, Alessandra Quercioli, Graziano Pelli, Sébastien Lenglet, Katia Galan, Fabienne Burger, Simonetta Calvo, Maria Bertolotto, Santina Bruzzone, Alberto Ballestrero, Franco Patrone, Franco Dallegri, Robson A.S. Santos, Nikolaos Stergiopulos, François Mach, Nicolas Vuilleumier, Fabrizio Montecucco, Alessio Nencioni   +24 more
openalex   +1 more source

NAD+ metabolism restriction boosts high-dose melphalan efficacy in patients with multiple myeloma

Blood Advances
: Elevated levels of the NAD+-generating enzyme nicotinamide phosphoribosyltransferase (NAMPT) are a common feature across numerous cancer types.
Debora Soncini, Pamela Becherini, Francesco Ladisa, Silvia Ravera, Adithya Chedere, Elisa Gelli, Giulia Giorgetti, Claudia Martinuzzi, Francesco Piacente, Luca Mastracci, Claudia Veneziano, Gianluca Santamaria, Fiammetta Monacelli, Moustafa S. Ghanem, Antonia Cagnetta, Fabio Guolo, Matteo Garibotto, Sara Aquino, Mario Passalaqua, Santina Bruzzone, Axel Bellotti, Michel A. Duchosal, Aimable Nahimana, Emanuele Angelucci, Chandra Nagasuma, Alessio Nencioni, Roberto Massimo Lemoli, Michele Cea   +27 more
doaj   +1 more source

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

eLife, 2017
Chemotherapy-induced peripheral neuropathy (CIPN) arises from collateral damage to peripheral afferent sensory neurons by anticancer pharmacotherapy, leading to debilitating neuropathic pain.
Peter M LoCoco, April L Risinger, Hudson R Smith, Teresa S Chavera, Kelly A Berg, William P Clarke   +5 more
doaj   +1 more source

Oversecretion and Overexpression of Nicotinamide Phosphoribosyltransferase/Pre-B Colony-Enhancing Factor/Visfatin in Inflammatory Bowel Disease Reflects the Disease Activity, Severity of Inflammatory Response and Hypoxia [PDF]

, 2019
Katarzyna Neubauer, Iwona Bednarz‐Misa, Ewa Wałecka-Zacharska, Jarosław Wierzbicki, Anil Agrawal, Andrzej Gamian, Małgorzata Krzystek−Korpacka   +6 more
openalex   +1 more source

Changes of Nicotinamide Phosphoribosyltransferase Expressions in Thyroid Glands of Patients with Different Thyroid Pathologies [PDF]

, 2018
Nadia Sawicka‐Gutaj, Mirosław Andrusiewicz, Agata Czarnywojtek, Joanna Waligórska‐Stachura, Maciej Biczysko, J Skrobisz, Jerzy Sowiński, Marek Ruchała   +7 more
openalex   +1 more source

Artificial Intelligence in Clinical and Translational Science: From Bench Insights to Bedside Impact

Clinical and Translational Science, Volume 18, Issue 11, November 2025.
Mohamed H. Shahin, Qi Liu
wiley   +1 more source

Nicotinamide Phosphoribosyltransferase in Smooth Muscle Cells Maintains Genome Integrity, Resists Aortic Medial Degeneration, and Is Suppressed in Human Thoracic Aortic Aneurysm Disease [PDF]

, 2017
Alanna Watson, Zengxuan Nong, Hao Yin, Caroline O’Neil, Stephanie A. Fox, Brittany Balint, Linrui Guo, Oberdan Léo, Michael Chu, Robert Gros, J. Geoffrey Pickering   +10 more
openalex   +1 more source

Cardiomyocyte Differentiation Promotes Cell Survival During Nicotinamide Phosphoribosyltransferase Inhibition Through Increased Maintenance of Cellular Energy Stores [PDF]

, 2017
Erin M. Kropp, Katarzyna A. Broniowska, Matthew Waas, Alyssa Nycz, John A. Corbett, Rebekah L. Gundry   +5 more
openalex   +1 more source