Results 121 to 130 of about 173,010 (312)

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

open access: yesEpilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin   +3 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Nicotine-evoked locomotion dose response curves in 36 and 48 hpf zebrafish embryos.

open access: yes, 2016
Nicotine dose response curves in 36 hpf (A and B) and 48 hpf (C and D) zebrafish embryos during the NLR. The NLR of 36 hpf embryos triggered by 240μM of nicotine was characterized by a significantly higher maximum speed than the observed in the rest of ...
Kurt R. Svoboda (2636239)   +2 more
core   +1 more source

Long‐Term Effectiveness of Inpatient and Day‐Hospital Treatment of Eating Disorders in Departments of Psychosomatic Medicine and Psychotherapy in Germany

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Background There is ample evidence on the efficacy of different therapeutic approaches in treating eating disorders. Yet, studies on the effectiveness of inpatient/day‐hospital treatment of eating disorders are rare. Method Data were retrieved from a naturalistic multi‐center effectiveness study of inpatient and day‐hospital treatment in ...
Magdalena Pape   +42 more
wiley   +1 more source

Augmenting varenicline treatment with transcranial direct current stimulation (tDCS) increases smoking abstinence rates at end of treatment

open access: yesBrain Stimulation, 2023
Helena Zhang   +5 more
doaj   +1 more source

Targeting the D3R-nAChR heteromeric complex for nicotine cessation

open access: yes, 2023
PPS17-4 Tobacco dependence remains one of the largest preventable causes of disease and death worldwide. Unfortunately, currently available therapeutics are only modestly ef- fective in assisting individuals to achieve long-term abstinence.
Clelia Dallanoce   +4 more
core  

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz   +4 more
wiley   +1 more source

Body‐integrated photonic biosensors: Illuminating the path to active healthcare

open access: yesFlexMat, EarlyView.
Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu   +10 more
wiley   +1 more source

Steady-state nicotine plasma levels following use of four different types of Swedish snus compared with 2-mg Nicorette chewing gum: A crossover study

open access: yes, 2005
The present study evaluated nicotine plasma levels achieved following 1 day's regular use of four commonly used brands of Swedish portion snus and 2-mg Nicorette chewing gum. The study also estimated the amount of sodium chloride extracted from each snus
Lunell, Erik,   +2 more
core   +1 more source

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