Results 101 to 110 of about 210,777 (258)
Protective Effect of Nicotine on Sepsis-Induced Oxidative Multiorgan Damage: Role of Neutrophils
, 2017 Despite its adverse health consequences, tobacco smoking is associated with lower incidence of several neurodegenerative and inflammatory diseases. The present study is aimed to show the effects of nicotine, major tobacco constituent, on five organs ...
ÖZBEYLİ, DİLEK +3 more
core +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
, 2019 INTRODUCTION:Existing treatments can aid tobacco smoking cessation, but they have low efficacy. Because there is a network of neural systems involved in tobacco addiction, combination treatments may provide greater efficacy.
Levin, Edward D +6 more
core +1 more source
Chemistry – A European Journal, EarlyView.Levamisole is a common adulterant found in street‐distributed cocaine. Molecular baskets have been shown to form stable inclusion complexes with both substances. While levamisole inserts its benzene into the basket's cavity, cocaine utilizes its bicyclic ring for encapsulation.
Christopher T. Mortensen +7 more
wiley +1 more source
A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids
Chemistry – A European Journal, EarlyView.This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci +8 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples +10 more
wiley +1 more source
, 2015 Introduction: Physical activity has been found to be related with many health benefits. Our aim was to investigate the effect of chronic moderate exercise from acute stress on nicotine and cigarette smoke exposed rats.
AKAKIN, DİLEK +3 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai +12 more
wiley +1 more source
Targeting the D3R-nAChR heteromeric complex for nicotine cessation
, 2023 PPS17-4 Tobacco dependence remains one of the largest preventable causes of disease and death worldwide. Unfortunately, currently available therapeutics are only modestly ef- fective in assisting individuals to achieve long-term abstinence.
Clelia Dallanoce +4 more
core +1 more source
Drug and Alcohol Dependence ReportsIn the past few years, technological advancements enabled the development of novel electronic nicotine delivery systems (ENDS). Several empirical measures such as “nicotine flux” are being proposed to evaluate the abuse liability potential of these ...
Aditya R. Kolli +7 more
doaj +1 more source