Results 111 to 120 of about 173,010 (312)

How Does Smoking and Nicotine Dependence Change After Onset of Vaping? A Retrospective Analysis of Dual Users

, 2020
Introduction: Although some smokers switch to exclusive use of electronic cigarettes (e-cigarettes), others become dual users of combustible cigarettes and e-cigarettes.
Martínez, Úrsula, Brandon, Karen O., Harrell, Paul T., Eissenberg, Thomas, Harrell, P. T., Brandon, Thomas H., Bullen, Christopher R., Brandon, T. H., Meltzer, L. R., Martínez Loredo, Víctor, Drobes, D. J., Bullen, C. R., Eissenberg, T., Drobes, David J., Simmons, Vani N., Simmons, V. N., Meltzer, Lauren R., Palmer, Amanda M., Martínez-Loredo, Víctor, Brandon, K. O., Palmer, A. M.   +20 more
core   +1 more source

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

Drug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis, Helen G. Gika, Georgios Panagiotoglou, Eleni Parlapani, Pavlos Pavlidis, Nikolaos Raikos   +5 more
wiley   +1 more source

Nicotine flux and pharmacokinetics-based considerations for early assessment of nicotine delivery systems

Drug and Alcohol Dependence Reports
In the past few years, technological advancements enabled the development of novel electronic nicotine delivery systems (ENDS). Several empirical measures such as “nicotine flux” are being proposed to evaluate the abuse liability potential of these ...
Aditya R. Kolli, Emilija Veljkovic, Florian Calvino-Martin, Marco Esposito, Arkadiusz K. Kuczaj, Ondrej Koumal, Jed E. Rose, Manuel C. Peitsch   +7 more
doaj   +1 more source

Nicotine and its effects on periodontal tissue

, 2018
Nicotine, the chief active ingredient of tobacco, has been known since the introduction of the plant in Europe in the middle sixteenth century. Nicotine can be found in some vegetables consumed in every-day life such as eggplant, cauliflower, green ...
Bassey-Duke, Amanda
core  

Free-Base and Total Nicotine, Reactive Oxygen Species, and Carbonyl Emissions from IQOS, a Heated Tobacco Product [PDF]

, 2019
Introduction: IQOS is an emerging heated tobacco product marketed by Philip Morris International (PMI). Because the tobacco in IQOS is electrically heated and not combusted, PMI claims that it generates significantly lower toxicant levels than ...
El-Hellani, Ahmad, Haddad, Christina, Talih, Soha, Karaoghlanian, Nareg, Saliba, Najat A., El-Hage, Rachel, Shihadeh, Alan Louis, Salman, Rola   +7 more
core   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

The in vitro effects of nicotine and selected antibiotics, tunicamycin and thapsigargin on human Breast carcinoma (mcf-7) cells. [PDF]

, 2012
>Magister Scientiae - MScCancer is defined as the abnormal growth of genetically mutated or perturbant cells. Nicotine is a known cancer promoter and an apoptotic suppressor.
Isaacs, Rabia
core   +1 more source

An update on nicotine replacement therapy

Journal of Oral Research and Review, 2019
Tobacco use is the single greatest preventable cause of death in the world. Most tobacco users want to quit but find it difficult to stop due to the addictiveness of nicotine. Interventions for tobacco cessation are important in enabling tobacco users to
K A Kamala, S Sankethguddad, S G Sujith
doaj   +1 more source

Addicted to Nicotine [PDF]

, 2010
Instead of sending you into convulsions, a cigarette can mellow you out and sharpen your mind.
Torrice, Michael M.
core  

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source