Results 31 to 40 of about 173,010 (312)
A Randomised trial of nicotine assisted reduction to stop in pharmacies - The RedPharm Study [PDF]
, 2012 Background Public policy and clinical treatment in tobacco addiction in the UK has focused on cessation: an abrupt attempt to stop all cigarettes. However, recent evidence suggests that allowing more gradual withdrawal from tobacco or even permanent ...
Rachel Bridson +31 more
core +1 more source
Pharmacological effects of nicotine salts on dopamine release in the nucleus accumbens
Frontiers in Pharmacology, 2023 With the growing number of individuals regularly using e-cigarettes, it has become increasingly important to understand the psychobiological effects of nicotine salts.
Xiaonan Li +9 more
doaj +1 more source
Neuron, 2009 Both conscious and unconscious memory mechanisms contribute to the rewarding effects of nicotine and other drugs of abuse. In this issue of Neuron, Tang and Dani use in vivo measures of synaptic plasticity in freely moving mice to link nicotine-induced dopamine release in hippocampus to LTP induction and behavioral reinforcement.
openaire +2 more sources
Effects of user puff topography, device voltage, and liquid nicotine concentration on electronic cigarette nicotine yield: Measurements and model predictions [PDF]
, 2015 Introduction: Some electronic cigarette (ECIG) users attain tobacco cigarette-like plasma nicotine concentrations while others do not. Understanding the factors that influence ECIG aerosol nicotine delivery is relevant to regulation, including product ...
Eissenberg, Thomas E. +8 more
core +1 more source
Differences in nicotine metabolism of two Nicotiana attenuata herbivores render them differentially susceptible to a common native predator. [PDF]
PLoS ONE, 2014 Nicotiana attenuata is attacked by larvae of both specialist (Manduca sexta) and generalist (Spodoptera exigua) lepidopteran herbivores in its native habitat. Nicotine is one of N. attenuata's important defenses. M.
Pavan Kumar +4 more
doaj +1 more source
Affective temperaments in nicotine-dependent and non-nicotine-dependent individuals [PDF]
, 2016 Background One of the smoking risk factors influencing nicotine dependency may be human personality; however, few studies have examined the association between Akiskal’s affective temperaments and smoking in adults.
Ewa Stanisławiak +1 more
core +1 more source
Frontiers in Molecular Neuroscience, 2023 IntroductionNicotine dependence is one of the main causes of preventable diseases in the United States. Nicotine-seeking and avoidance behavioral assays in larval zebrafish could be used for identifying potential new pharmacotherapeutics in an early ...
Henning Schneider +6 more
doaj +1 more source
, 2012 Nicotine is known to enhance long-term hippocampus dependent learning and memory in both rodents and humans via its activity at nicotinic acetylcholinergic receptors (nAChRs).
Rachel L Poole +14 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Trials, 2017 Background Delivering effective tobacco dependence treatment that is feasible within lung cancer screening (LCS) programs is crucial for realizing the health benefits and cost savings of screening.
Amanda L. Graham +12 more
doaj +1 more source