Results 41 to 50 of about 210,777 (258)

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Zammit, Christian, Zammit C, Di Giovanni, Giuseppe, Muscat, Richard, Pitruzzella A, Muscat R, Pierucci M, Valentino, Mario, Benigno, Arcangelo, Di Giovanni G., Pierucci, Massimo, Valentino M, Pitruzzella, Alessandro   +12 more
core  

A Randomised trial of nicotine assisted reduction to stop in pharmacies - The RedPharm Study [PDF]

, 2012
Background Public policy and clinical treatment in tobacco addiction in the UK has focused on cessation: an abrupt attempt to stop all cigarettes. However, recent evidence suggests that allowing more gradual withdrawal from tobacco or even permanent ...
Rachel Bridson, Coleman, T, Etter, Jean-Francois, Clarke Sarah, Macaskill, Susan, MacAskill Susan, Taskila, T, Jean-Francois Etter, Clarke, Sarah, Bridson, Rachel, Taskila, Taina, Taskila Taina, Susan MacAskill, Macaskill, S, Mahendra Patel, Patel, Mahendra, Coleman Tim, Coleman, Tim, Patel, M, Aveyard Paul, Etter, JF, Patel Mahendra, Aveyard, P, Bridson, R, Bridson Rachel, Paul Aveyard, Etter Jean-Francois, Sarah Clarke, Tim Coleman, Clarke, S, Taina Taskila, Aveyard, Paul   +31 more
core   +2 more sources

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

Advanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn, Min‐seop Kim, Ju‐Hee Kim, Seok‐Hyeon Kang, Dain Lee, Hui‐Wen Liu, Seung‐cheol Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong, Ji Hun Yang, Jin‐A Kim, Hwanseok Jang, Hong Nam Kim, Roger D. Kamm, Ji‐Hoon Kim, Jang‐Won Son, Seok Chung   +17 more
wiley   +1 more source

Reward responsivity and the development of nicotine dependence

, 2008
Different theories have been proposed to explain the development of nicotine dependence. Some theories suggest that nicotine has direct reinforcing properties, either positive or negative.
Kalamboka, Natasha
core   +1 more source

Accelerating tobacco regulatory science in the United States: The center for rapid surveillance of tobacco

Preventive Medicine Reports
The U.S. tobacco marketplace has undergone rapid and profound change over the past decade, marked by the emergence of new product categories, brands, and marketing strategies that challenge traditional public health surveillance.
Cristine D. Delnevo, Ollie Ganz, Patrick Barnwell, Heidi Seabrooks-Smith, Kathyrn Edwards   +4 more
doaj   +1 more source

Comparative evaluation of the efficacy of nicotine chewing gum and nicotine patches as nicotine replacement therapy using salivary cotinine levels as a biochemical validation measure

Indian Journal of Psychiatry, 2023
Background: Nicotine replacement therapy (NRT) and habit cessation counseling are considered the mainstay treatment for high nicotine dependence smokers. However, adherence to NRT is very poor.
T Sivasankari, Avudaiappan Sankaran, Senthil Murugappan, Veni Subramanyam, Balanehru Subramanian, RC Jagat Reddy, S Vandana   +6 more
doaj   +1 more source

Effects of user puff topography, device voltage, and liquid nicotine concentration on electronic cigarette nicotine yield: Measurements and model predictions [PDF]

, 2015
Introduction: Some electronic cigarette (ECIG) users attain tobacco cigarette-like plasma nicotine concentrations while others do not. Understanding the factors that influence ECIG aerosol nicotine delivery is relevant to regulation, including product ...
Eissenberg, Thomas E., El-Hellani, Ahmad, Baalbaki, Rima, Talih, Soha, Karaoghlanian, Nareg, Saliba, Najat A., Balhas, Zainab, Shihadeh, Alan Louis, Salman, Rola   +8 more
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

“We’re building the plane while we’re flying it”: perspectives on local cigar policy implementation from qualitative interviews with key personnel

Implementation Science Communications
Background Nearly 300 US municipalities have enacted policies regulating cigar pack size and price to reduce youth access to and use of inexpensive cigars.
Jessica King Jensen, Kathryn LaCapria, Stefanie Gratale, Myneka Macenat, Jeanne M. Ferrante, Alexandra McGarry Williams, Hassiet Asberom, Cristine D. Delnevo, Sunday Azagba   +8 more
doaj   +1 more source

Association between exposure to digital alcohol marketing and alcohol use: a systematic review and meta-analysis

The Lancet Public Health
Summary: Background: Exposure to digital alcohol marketing content might be associated with pro-alcohol-related attitudes and behaviours, including the likelihood of initiating or sustaining the use of alcohol, especially among adolescents (aged
Scott I Donaldson, PhD, Alex M Russell, PhD, Kathryn La Capria, MPH, Amanda DeJesus, MA, Emily Wang, Jamil Fayad, Jon-Patrick Allem, PhD   +6 more
doaj   +1 more source