Results 41 to 50 of about 173,010 (312)

Comparative evaluation of the efficacy of nicotine chewing gum and nicotine patches as nicotine replacement therapy using salivary cotinine levels as a biochemical validation measure

Indian Journal of Psychiatry, 2023
Background: Nicotine replacement therapy (NRT) and habit cessation counseling are considered the mainstay treatment for high nicotine dependence smokers. However, adherence to NRT is very poor.
T Sivasankari, Avudaiappan Sankaran, Senthil Murugappan, Veni Subramanyam, Balanehru Subramanian, RC Jagat Reddy, S Vandana   +6 more
doaj   +1 more source

Nicotine strongly activates dendritic cell-mediated adaptive immunity - potential role for progression of atherosclerotic lesions

, 2003
Background - Antigen-presenting cells (APCs) such as monocytes and dendritic cells (DCs) stimulate T-cell proliferation and activation in the course of adaptive immunity.
Dimmeler, S, Heeschen, C, Andreas M. Zeiher, Alexandra Aicher, Cooke, JP, Mariette Mohaupt, Aicher, A, Aicher, A., Christopher Heeschen, Stefanie Dimmeler, John P. Cooke, Zeiher, A.M., Heeschen, C., Dimmeler, S., Mohaupt, M, Mohaupt, M., Zeiher, AM, Cooke, J.P.   +17 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Nicotine and carbonyl emissions from popular electronic cigarette products: Correlation to liquid composition and design characteristics [PDF]

, 2018
Introduction: Available in hundreds of device designs and thousands of flavors, electronic cigarette (ECIG) may have differing toxicant emission characteristics.
El-Hellani, Ahmad, Baalbaki, Rima, Malek, Nathalie J., Nakkash, Rima T., Talih, Soha, Karaoghlanian, Nareg, Saliba, Najat A., El-Hage, Rachel, Shihadeh, Alan Louis, Salman, Rola   +9 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Trajectories of lifetime vaping in teens and young adults: latent transition analyses over one year

BMC Public Health
Background Despite the bidirectional relationship between initiation of cannabis and nicotine vaping, little is known about the patterns of vaping experimentation and progression among young people.
Allison M. Glasser, Marisa Tomaino, Caitlin Uriarte, Chelsea Carman, Maria Roemhildt, Rhonda Williams, Julia Chen-Sankey, Andrea C. Villanti   +7 more
doaj   +1 more source

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Zammit, Christian, Zammit C, Di Giovanni, Giuseppe, Muscat, Richard, Pitruzzella A, Muscat R, Pierucci M, Valentino, Mario, Benigno, Arcangelo, Di Giovanni G., Pierucci, Massimo, Valentino M, Pitruzzella, Alessandro   +12 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Identifying determinants of varenicline adherence using the Theoretical Domains framework: a rapid review

BMC Public Health
Background Adhering to varenicline has been shown to significantly improve the chances of successfully quitting smoking, with studies indicating a twofold increase in 6-month quit rates.
Nadia Minian, Melissa Wong, Sowsan Hafuth, Terri Rodak, Alma Rahimi, Dea Gjomema, Jonathan Rose, Laurie Zawertailo, Matt Ratto, Peter Selby   +9 more
doaj   +1 more source

SMART goals setting and biometric changes in obese adults with multimorbidity: Secondary analysis of a randomized controlled trial

SAGE Open Medicine, 2019
Objectives: Clinicians recommend diet and exercise for overweight/obese patients. We conducted a secondary analysis of a randomized controlled clinical trial evaluating goal setting and pedometer use versus usual care on weight, waist circumference, and ...
Paul Y Takahashi, Stephanie M Quigg, Ivana T Croghan, Darrell R Schroeder, Jon O Ebbert   +4 more
doaj   +1 more source