Results 51 to 60 of about 210,777 (258)

Affective temperaments in nicotine-dependent and non-nicotine-dependent individuals [PDF]

, 2016
Background One of the smoking risk factors influencing nicotine dependency may be human personality; however, few studies have examined the association between Akiskal’s affective temperaments and smoking in adults.
Ewa Stanisławiak, Włodzimierz Oniszczenko   +1 more
core   +1 more source

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

Advanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng, Masaki Nasu, Ayman Abdul‐Ghani, Yu Chen, Shaoqiu Chen, Isam Mohd Ibrahim, Hanqiu Zhang, Lauren Higa, Zitong Gao, Hua Yang, Raphael Bueno, Loïc Le Marchand, Youping Deng   +12 more
wiley   +1 more source

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

Advanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi, Federica Cherchi, Martina Venturini, Federico Tommasi, Sandro Gonzi, Chiara Capacci, Giulia Guarnieri, Pasquale Gallina, Annamaria Morelli, Anna Maria Pugliese   +9 more
wiley   +1 more source

Triangulating youth tobacco use and product appeal for rapid surveillance: Findings from three online surveys

Preventive Medicine Reports
Objective: Understanding youth tobacco use is essential to informing timely regulatory and public health responses. Triangulating traditional nationally representative survey results with more rapid and flexible survey data can provide important interim ...
Lauren R. Pacek, Olivia A. Wackowski, Patrick V. Barnwell, Cristine D. Delnevo   +3 more
doaj   +1 more source

SMART goals setting and biometric changes in obese adults with multimorbidity: Secondary analysis of a randomized controlled trial

SAGE Open Medicine, 2019
Objectives: Clinicians recommend diet and exercise for overweight/obese patients. We conducted a secondary analysis of a randomized controlled clinical trial evaluating goal setting and pedometer use versus usual care on weight, waist circumference, and ...
Paul Y Takahashi, Stephanie M Quigg, Ivana T Croghan, Darrell R Schroeder, Jon O Ebbert   +4 more
doaj   +1 more source

Rapid reduction versus abrupt quitting for smokers who want to stop soon: a randomised controlled non-inferiority trial [PDF]

, 2009
Background: The standard way to stop smoking is to stop abruptly on a quit day with no prior reduction in consumption of cigarettes. Many smokers feel that reduction is natural and if reduction programmes were offered, many more might take up treatment ...
Lindson, N, Ingram, JT, Robert West, West, R, Susan Michie, Jennie Inglis, Ingram Jackie T, Jane Beach, Lindson, Nicola, Inglis, Jennie, Lindson Nicola, Aveyard Paul, West Robert, Michie, S, Aveyard, P, Michie, Susan, West, Robert, Paul Aveyard, Inglis, J, Beach Jane, Beach, Jane, Ingram, Jackie T., Ingram, Jackie, Ingram, Jackie T, Inglis Jennie, Nicola Lindson, Jackie T Ingram, Aveyard, Paul, Beach, J, Michie Susan   +29 more
core   +3 more sources

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

Advanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He, Hejun Ren, Shuo Zhang, Jikang Cheng, Hui Zhang, Jiao Liu, Sijie Wang, Congfen Gao, Yanchao Zhang, Yunhao Gao   +9 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Monitoring of tobacco product marketing for rapid public health surveillance in the United States

Preventive Medicine Reports
The US tobacco landscape is constantly changing, with the commercial tobacco industry regularly flooding the market with new brands, flavors, and styles.
Ollie Ganz, Jon-Patrick Allem, Meagan O. Robichaud, Eugene M. Talbot, Kristopher Roberts, Patrick V. Barnwell, Scott I. Donaldson, Cristine D. Delnevo   +7 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source