Results 61 to 70 of about 173,010 (312)

Nicotine delivery and user ratings of IQOS heated tobacco system compared to cigarettes, Juul and refillable e-cigarettes.

, 2021
INTRODUCTION: Reduced-risk nicotine products are more likely to replace smoking if they match cigarettes in nicotine delivery and user satisfaction. We examined the nicotine delivery profile and user ratings of IQOS heated tobacco system and compared it ...
Pesola, F, Hajek, P, Phillips-Waller, A, Przulj, D, Myers Smith, K   +4 more
core   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Identification and Quantitation of Nicotine Polacrilex in Nicotine Pouches and Other Oral Nicotine Delivery Products

Contributions to Tobacco and Nicotine Research, 2023
Nicotine polacrilex (CAS-No. 96055-45-7) can be used as the source of nicotine in nicotine pouches and other oral nicotine delivery products such as lozenges, tablets, and gums.
Moldoveanu Serban C.
doaj   +1 more source

Effect of nicotine and muscle performance using a Wingate Anaerobic Test on collegiate football players [PDF]

, 2006
Nicotine is a naturally occurring addictive alkaloid and in some cases, a lethal drug. The long-term harmful effects of nicotine have been widely documented through means of publications, commercials and even billboards to stop the use of nicotine in the
Meier, Joel N.
core  

Nicotine

, 2018
Nicotine content in the leaf and root tissue of the ...
Susanne Wurst (282824), Dinesh Kafle (3728908)   +1 more
core   +1 more source

Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary.

, 2022
This commentary addresses critical questions regarding the impact of the reduction of nicotine on changes in smoking behavior. There appears to be moderate evidence that use of reduced nicotine cigarettes (RNC) increases the likelihood of making a quit ...
Piper, Megan E, Drobes, David J, Walker, Natalie   +2 more
core   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Youth attention, perceptions, and appeal in response to e-cigarette advertising features: A focus group study

Preventive Medicine Reports
Background: E-cigarette marketing exposure may influence vaping-related outcomes among youth, but less is known on which specific advertising features impact youth attention, perceptions, and appeal.
Michelle Jeong, Caitlin Weiger, Caitlin Uriarte, Olivia A. Wackowski, Cristine D. Delnevo   +4 more
doaj   +1 more source

Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use and compulsive smoking

Frontiers in Psychiatry, 2013
Much evidence indicates that individuals use tobacco primarily to experience the psychopharmacological properties of nicotine and that a large proportion of smokers eventually become dependent on nicotine.
Ami eCohen, Olivier eGeorge
doaj   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source