Results 1 to 10 of about 38,909 (257)

Multifactorial Etiology of Adolescent Nicotine Addiction: A Review of the Neurobiology of Nicotine Addiction and Its Implications for Smoking Cessation Pharmacotherapy [PDF]

Frontiers in Public Health, 2021
Nicotine is the primary pharmacologic component of tobacco, and its highly addictive nature is responsible for its widespread use and significant withdrawal effects that result in challenges to smoking cessation therapeutics.
Supriya D. Mahajan, Gregory G. Homish, Amanda Quisenberry   +2 more
doaj   +2 more sources

Hippocampal Metabolomics Reveal the Mechanism of α-Conotoxin [S9K]TxID Attenuating Nicotine Addiction [PDF]

Marine Drugs
Nicotine is the main substance responsible for the development of tobacco addiction. The α3β4 nicotinic acetylcholine receptors (nAChRs) are a potential key target for mitigating nicotine reward.
Meiting Wang, Weifeng Xu, Huanbai Wang, Cheng Cui, Rongyan He, Xiaodan Li, Jinpeng Yu, J. Michael McIntosh, Dongting Zhangsun, Sulan Luo   +9 more
doaj   +2 more sources

Mechanisms of Nicotine Addiction. [PDF]

Cold Spring Harb Perspect Med, 2021
Tobacco smoking results in more than five million deaths each year and accounts for ∼90% of all deaths from lung cancer.3 Nicotine, the major reinforcing component of tobacco smoke, acts in the brain through the neuronal nicotinic acetylcholine receptors (nAChRs).
Picciotto MR, Kenny PJ.
europepmc   +4 more sources

Nicotine and neuronal nicotinic acetylcholine receptors: unraveling the mechanisms of nicotine addiction [PDF]

Frontiers in Neuroscience
Nicotine, recognized as the principal addictive component in tobacco, is mechanistically linked to its interaction with neuronal nicotinic acetylcholine receptors (nAChRs).
Jian Jiang, Xia Li, An-fu Hu, Guo-jun Zhou, Yi-han Gao, Chengyun Xu, Xi-mei Wu, Hong-Juan Wang   +7 more
doaj   +2 more sources

Assessing Perceptions and Behaviors Related to Vaping Nicotine: The Nicotine Addiction Perceptions Scale [PDF]

Tobacco Use Insights
Background Existent research examining perceptions of nicotine addiction use largely surface level items that fail to address the complexity of nicotine addiction.
Allison A. Temourian, Anna V. Song, Anna E. Epperson   +2 more
doaj   +2 more sources

Combining neuroimaging and brain stimulation to test alternative causal pathways for nicotine addiction in schizophrenia [PDF]

Brain Stimulation
The smoking rate is high in patients with schizophrenia. Brain stimulation targeting conventional brain circuits associated with nicotine addiction has also yielded mixed results.
Xiaoming Du, Fow-Sen Choa, Joshua Chiappelli, Heather Bruce, Mark Kvarta, Ann Summerfelt, Yizhou Ma, William T. Regenold, Kevin Walton, George F. Wittenberg, Stephanie Hare, Si Gao, Andrew van der Vaart, Zhiwei Zhao, Shuo Chen, Peter Kochunov, L. Elliot Hong   +16 more
doaj   +2 more sources

A single-center case-control study of the association between dorsal striatal damage and nicotine addiction [PDF]

Frontiers in Neurology
BackgroundSmoking is closely linked to pulmonary diseases, cardiovascular diseases, cancer, and other health issues, posing a significant threat to human health.
Chuya Jing, Chuya Jing, Chuya Jing, Chuya Jing, Chuya Jing, Xingkai An, Xingkai An, Xingkai An, Xingkai An, Xingkai An, Xingkai An, Xingkai An, Jie Fang, Jie Fang, Jie Fang, Jie Fang, Jie Fang, Jie Fang, Jie Fang, Jie Fang, Jie Fang   +20 more
doaj   +2 more sources

The interaction of oxytocin and nicotine addiction on psychosocial stress: an fMRI study [PDF]

Translational Psychiatry
The anxiolytic effect of oxytocin (OXT) on psychosocial stress has been well documented, but the effectiveness under the interference of other factors still requires in-depth research.
Jiecheng Ren, Yuting Zhang, Hongwen Song, Huixing Gou, Qian Zhao, Wei Hong, Yi Piao, Yucan Chen, Yijun Chen, Shilin Wen, Zhangxin Du, Chuanfu Li, Bensheng Qiu, Yina Ma, Xiaochu Zhang, Zhengde Wei   +15 more
doaj   +2 more sources

Engaging a person with lived experience of mental illness in a collaborative care model feasibility study

Research Involvement and Engagement, 2021
Plain English summary Researchers have explored different types of treatment to help people with a mental illness with other problems they might be experiencing, such as their health condition and quality of life.
Lenka Vojtila, Iqra Ashfaq, Augustina Ampofo, Danielle Dawson, Peter Selby   +4 more
doaj   +1 more source

The effectiveness of generic emails versus a remote knowledge broker to integrate mood management into a smoking cessation programme in team-based primary care: a cluster randomised trial

Implementation Science, 2021
Background Knowledge brokering is a knowledge translation approach that has been gaining popularity in Canada although the effectiveness is unknown.
Nadia Minian, Sheleza Ahad, Anna Ivanova, Scott Veldhuizen, Laurie Zawertailo, Arun Ravindran, Claire de Oliveira, Dolly Baliunas, Carol Mulder, Corneliu Bolbocean, Peter Selby   +10 more
doaj   +1 more source