Results 41 to 50 of about 44,965 (296)

The orexin system and nicotine addiction: preclinical insights [PDF]

, 2019
Current pharmacotherapies for smoking have only modest efficacy with failure rates of up to 90%. One potential target for new pharmacotherapies is the orexin/hypocretin system, a hypothalamic neuropeptide system involved in arousal, appetite and reward ...
Khoo, Shaun, McNally, Gavan, Kelly J. Clemens, Clemens, Kelly ; https://orcid.org/, Gavan P. McNally, Khoo, S ; https://orcid.org/, McNally, Gavan ; https://orcid.org/, Shaun Yon-Seng Khoo, Clemens, Kelly   +8 more
core   +1 more source

Carryover effects to addiction-associated stimuli in a group of marijuana and cocaine users [PDF]

, 2010
Addiction has been characterized as an attentional bias towards drug-related cues. In two experiments we investigate the effects of non-words that have been associatively trained to addiction-related images in a group of marijuana and cocaine users ...
Money, Sharon, Sharma, Dinkar
core   +1 more source

Improved treatment of nicotine addiction and emerging pulmonary drug delivery

, 2012
Nicotine addiction remains the leading cause of death and disease in developed and developing nations and a major cause of mortality around the world.
Rahman, Shafiqur, Islam, Nazrul
core   +1 more source

Internet addiction in students: prevalence and risk factors [PDF]

, 2013
The last decade has witnessed a large increase in research on the newly emerging mental health problem of Internet addiction. Rather than looking at Internet addiction per se, this study focused on particular activities on the Internet that might be ...
Kuss, DJ, Griffiths, MD, Binder, JF
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

A Study on Nicotine Dependency Levels of Smoking University Students Depending On Socio-Demographic Features, and Smoking Habits

Tobacco Induced Diseases, 2018
Smoking is a common addictive behavior found among young people particularly university students. In the case of smoking addiction the substance nicotine has the most important influence. Therefore, in the fight against smoking addiction it is considered
Canan Yoruk, Görkem Yararbas
doaj   +1 more source

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Zammit, Christian, Zammit C, Di Giovanni, Giuseppe, Muscat, Richard, Pitruzzella A, Muscat R, Pierucci M, Valentino, Mario, Benigno, Arcangelo, Di Giovanni G., Pierucci, Massimo, Valentino M, Pitruzzella, Alessandro   +12 more
core  

Rapid reduction versus abrupt quitting for smokers who want to stop soon: a randomised controlled non-inferiority trial

, 2009
Background: The standard way to stop smoking is to stop abruptly on a quit day with no prior reduction in consumption of cigarettes. Many smokers feel that reduction is natural and if reduction programmes were offered, many more might take up treatment ...
Lindson, N, Ingram, JT, Robert West, West, R, Susan Michie, Jennie Inglis, Ingram Jackie T, Jane Beach, Lindson, Nicola, Inglis, Jennie, Lindson Nicola, Aveyard Paul, West Robert, Michie, S, Aveyard, P, Michie, Susan, West, Robert, Paul Aveyard, Inglis, J, Beach Jane, Beach, Jane, Ingram, Jackie T., Ingram, Jackie, Ingram, Jackie T, Inglis Jennie, Nicola Lindson, Jackie T Ingram, Aveyard, Paul, Beach, J, Michie Susan   +29 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

If the data contradict the theory, throw out the data: Nicotine addiction in the 2010 report of the Surgeon General

Harm Reduction Journal, 2011
The reports of US Surgeon General on smoking are considered the authoritative statement on the scientific state of the art in this field. The previous report on nicotine addiction published in 1988 is one of the most cited references in scientific ...
Frenk Hanan, Dar Reuven
doaj   +1 more source