Results 51 to 60 of about 265,934 (241)

An analytical study of etiopathological factors responsible for oral squamous cell carcinoma in Bihar population

Journal of Pharmacy and Bioallied Sciences, 2020
Background: Squamous cell carcinoma (SCC) of maxillofacial region is the most usual form of neoplasia causing malignancies in India and Asian continent.
Tanoj Kumar, Sanjay Manohar Kanade, Rohit Singh, Alisha Singh, Avanindra Kumar, Vardar R Hiremath   +5 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Cue reactivity in nicotine and alcohol addiction: a cross-cultural view

Frontiers in Psychology, 2016
A wealth of research indicates that cue reactivity is critical to understanding the neurobiology of nicotine and alcohol addiction and developing treatments.
Wanwan Lv, Qichao Wu, Xiaoming Liu, Ying Chen, Hongwen Song, Li-Zhuang Yang, Xiaochu Zhang   +6 more
doaj   +1 more source

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

Advanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng, Masaki Nasu, Ayman Abdul‐Ghani, Yu Chen, Shaoqiu Chen, Isam Mohd Ibrahim, Hanqiu Zhang, Lauren Higa, Zitong Gao, Hua Yang, Raphael Bueno, Loïc Le Marchand, Youping Deng   +12 more
wiley   +1 more source

Study protocol for a non-inferiority trial of cytisine versus nicotine replacement therapy in people motivated to stop smoking [PDF]

, 2011
Background Smokers need effective support to maximise the chances of successful quit attempts. Current smoking cessation medications, such as nicotine replacement therapy (NRT), bupropion, nortriptyline or varenicline, have been shown to be effective in ...
Hayden McRobbie, Nosa, Vili, Nosa, V, Walker, N, Glover, M, Howe Colin, Joanne Barnes, Bullen, C, Glover Marewa, McRobbie Hayden, Jonathan Williman, McRobbie, H, Barnes, J, Howe, C, Walker Natalie, Colin Howe, Williman, J, Bullen, Christopher, Parag, Varsha, Bullen Chris, Reon Veale, Greenaway, Natalie, Varsha Parag, Glover, Marewa, Natalie Walker, Parag Varsha, Veale Reon, Marewa Glover, Barnes, Joanne, Vili Nosa, Veale, R, Parag, V, Williman Jonathan, Williman, Jonathan, Nosa Vili, Chris Bullen, Barnes Joanne   +36 more
core   +2 more sources

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

Advanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi, Federica Cherchi, Martina Venturini, Federico Tommasi, Sandro Gonzi, Chiara Capacci, Giulia Guarnieri, Pasquale Gallina, Annamaria Morelli, Anna Maria Pugliese   +9 more
wiley   +1 more source

Study protocol for a randomised controlled trial of electronic cigarettes versus nicotine patch for smoking cessation [PDF]

, 2013
PMCID: PMC3602285This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Hayden McRobbie, Varsha Parag, Natalie Walker, Murray Laugesen, Walker, N, Bullen, C, Parag, V, Laugesen, M, Jonathan Williman, McRobbie, H, Chris Bullen, Howe, C, Colin Howe, Williman, J   +13 more
core   +2 more sources

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

Advanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He, Hejun Ren, Shuo Zhang, Jikang Cheng, Hui Zhang, Jiao Liu, Sijie Wang, Congfen Gao, Yanchao Zhang, Yunhao Gao   +9 more
wiley   +1 more source

A pilot randomised controlled trial of the feasibility of using body scan and isometric exercises for reducing urge to smoke in a smoking cessation clinic. [PDF]

, 2008
BACKGROUND: The main cause of relapse in smokers attempting to quit is inability to resist urges to smoke. Pharmacotherapy ameliorates but does not entirely prevent urges to smoke when abstinent, so other methods to resist urges to smoke might be helpful.
Stenner, S, Neha Prasad, Stenner, Sarah, Michael Ussher, Lemees Al-Chalabi, Prasad, Neha, Ussher, M, Prasad Neha, Steed, Lucy, Jane Beach, Al-Chalabi, L, Stenner Sarah, Al-Chalabi Lemees, Aveyard Paul, Prasad, N, Aveyard, P, Paul Aveyard, Beach Jane, Beach, Jane, Al-Chalabi, Lemees, Steed Lucy, Ussher, Michael, Ussher Michael, Steed, L, Beach, J, Aveyard, Paul, Lucy Steed, Sarah Stenner   +27 more
core   +2 more sources

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source