Results 31 to 40 of about 44,965 (296)

A Randomised trial of nicotine assisted reduction to stop in pharmacies - The RedPharm Study [PDF]

, 2012
Background Public policy and clinical treatment in tobacco addiction in the UK has focused on cessation: an abrupt attempt to stop all cigarettes. However, recent evidence suggests that allowing more gradual withdrawal from tobacco or even permanent ...
Rachel Bridson, Coleman, T, Etter, Jean-Francois, Clarke Sarah, Macaskill, Susan, MacAskill Susan, Taskila, T, Jean-Francois Etter, Clarke, Sarah, Bridson, Rachel, Taskila, Taina, Taskila Taina, Susan MacAskill, Macaskill, S, Mahendra Patel, Patel, Mahendra, Coleman Tim, Coleman, Tim, Patel, M, Aveyard Paul, Etter, JF, Patel Mahendra, Aveyard, P, Bridson, R, Bridson Rachel, Paul Aveyard, Etter Jean-Francois, Sarah Clarke, Tim Coleman, Clarke, S, Taina Taskila, Aveyard, Paul   +31 more
core   +1 more source

The effect of a clinical decision support system on prompting an intervention for risky alcohol use in a primary care smoking cessation program: a cluster randomized trial

Implementation Science, 2019
Background Clinical decision support systems (CDSSs) may promote practitioner adherence to evidence-based guidelines. This study examined if the addition of a CDSS influenced practitioner delivery of a brief intervention with treatment-seeking smokers ...
Nadia Minian, Dolly Baliunas, Aliya Noormohamed, Laurie Zawertailo, Norman Giesbrecht, Christian S. Hendershot, Bernard Le Foll, Jürgen Rehm, Andriy V. Samokhvalov, Peter L. Selby   +9 more
doaj   +1 more source

Predisposing and protective factors influencing suicide ideation, attempt, and death in patients accessing substance use treatment: a systematic review and meta-analysis protocol

Systematic Reviews, 2019
Background The lifetime risk of suicide in patients with substance use disorder is five to ten times the risk in the general population. Critically, up to 19% of patients continue to think about and attempt suicide even after accessing treatment ...
S. Espinet, T. Corrin, D. Baliunas, L. Quilty, L. Zawertailo, S. J. Rizvi, W. deRuiter, S. Bonato, V. De Luca, S. Kennedy, P. Selby   +10 more
doaj   +1 more source

Genetic influences impacting nicotine use and abuse during adolescence: Insights from human and rodent studies

Brain Research Bulletin, 2022
Nicotine use continues to be a major public health concern, with an alarming recent rise in electronic cigarette consumption. Heritability estimates of nicotine use and abuse range from 40% to 80%, providing strong evidence that genetic factors impact ...
Lisa R. Goldberg, Thomas J. Gould
doaj   +1 more source

Relapse to smoking during unaided cessation: clinical, cognitive and motivational predictors [PDF]

, 2010
Rationale: Neurobiological models of addiction suggest that abnormalities of brain reward circuitry distort salience attribution and inhibitory control processes, which in turn contribute to high relapse rates.
Jane Powell, John Powell, Powell, Jane, Powell, John, Lynne Dawkins, Alan Pickering, West, Robert, Robert West, Dawkins, Lynne, Powell, John; id_orcid, Powell, Jane H., Pickering, Alan   +11 more
core   +1 more source

LEVELS OF NICOTINE ADDICTION IN CONSUMERS OF THE LATEST TOBACCO PRODUCTS

Acta Medica Leopoliensia, 2023
Aim. Determining the level of nicotine addiction in consumers of the latest tobacco products. Materials and Methods. We have surveyed 817 young people (from 18 to 45 years of age) living in Lviv region. Among them, two focus groups were distinguished:
Svitlana Kozii-Bredelieva, Iryna Kovalska   +1 more
doaj   +1 more source

Nicotine and e-cigarettes addiction [PDF]

, 2020
Tobacco use claims more than 8 million lives annually, with most tobacco-related deaths occurring in low and middle-income countries. Second-hand tobacco smoke contributes to an additional 1.2 million deaths annually due to heart disease, cancer, and ...
Ahmad Basri, Nadzirah, Abdul Rahman Ahmad Badayai, Ahmad Badayai, Abdul Rahman, Essau, Cecilia; id_orcid, Cecilia A. Essau, Wahab, Suzaily, Nadzirah Ahmad Basri, Essau, Cecilia A., Suzaily Wahab   +8 more
core   +1 more source

Study protocol for a non-inferiority trial of cytisine versus nicotine replacement therapy in people motivated to stop smoking [PDF]

, 2011
Background Smokers need effective support to maximise the chances of successful quit attempts. Current smoking cessation medications, such as nicotine replacement therapy (NRT), bupropion, nortriptyline or varenicline, have been shown to be effective in ...
Hayden McRobbie, Nosa, Vili, Nosa, V, Walker, N, Glover, M, Howe Colin, Joanne Barnes, Bullen, C, Glover Marewa, McRobbie Hayden, Jonathan Williman, McRobbie, H, Barnes, J, Howe, C, Walker Natalie, Colin Howe, Williman, J, Bullen, Christopher, Parag, Varsha, Bullen Chris, Reon Veale, Greenaway, Natalie, Varsha Parag, Glover, Marewa, Natalie Walker, Parag Varsha, Veale Reon, Marewa Glover, Barnes, Joanne, Vili Nosa, Veale, R, Parag, V, Williman Jonathan, Williman, Jonathan, Nosa Vili, Chris Bullen, Barnes Joanne   +36 more
core   +1 more source

Personalized dosing of nicotine replacement therapy versus standard dosing for the treatment of individuals with tobacco dependence: study protocol for a randomized placebo-controlled trial

Trials, 2020
Background Medications for smoking cessation are currently only effective in helping a minority of smokers quit. Drug development is slow and expensive; as such, there is much interest in optimizing the effectiveness of existing treatments and ...
Laurie Zawertailo, Christian S. Hendershot, Rachel F. Tyndale, Bernard Le Foll, Andriy V. Samokhvalov, Kevin E. Thorpe, Andrew Pipe, Robert D. Reid, Peter Selby   +8 more
doaj   +1 more source

SUATU KAJIAN MOLEKULER KETERGANTUNGAN NIKOTIN

Jurnal Farmasi Sains dan Komunitas, 2016
: Nicotine, a simple chemical substance from tobacco, stimulates addiction by neuroadaptation inducing rewards system in human brain. Molecular mechanism of nicotine addiction in rewards system are mediated by nicotinic acetylcholine receptor (nAChR) and 
Agustina Setiawati
doaj   +1 more source