Results 131 to 140 of about 3,355,558 (275)

Association of Life's Essential 8 Score With Incident Pancreatic Cancer: A Prospective Cohort Study in Shanghai, China

open access: yesCancer Science, EarlyView.
In this prospective cohort study of 60,556 cancer‐free adults with a median follow‐up of 7.44 years, a higher Life's Essential 8 (LE8) score, reflecting better cardiovascular health, was associated with a lower risk of pancreatic cancer (PC). Each 1‐SD increase in LE8 score was associated with an 18% lower PC risk.
Liping Yi   +8 more
wiley   +1 more source

Reduced Risk of MASLD and Cardiometabolic Disease Following Renal Denervation Therapy in Patients With Resistant Hypertension

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Autonomic dysfunction increases the risk of cardio‐kidney‐metabolic (CKM) syndrome including metabolic dysfunction‐associated steatotic liver disease (MASLD), type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease (CKD).
Alex E. Henney   +8 more
wiley   +1 more source

Neuropsychiatric Outcomes Associated With GLP‐1 Receptor Agonist Use in Medicare Beneficiaries With Type 2 Diabetes: Variation by Treatment Pattern and Obesity Status

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptors are expressed in brain regions governing mood, reward and stress, yet the neuropsychiatric effects of GLP‐1 receptor agonist (GLP‐1 RA) therapy remain poorly characterized. We estimated associations between GLP‐1 RA use and neuropsychiatric disorders and variation by obesity status and treatment ...
Seo Hyon Baik   +4 more
wiley   +1 more source

Female genital lichen sclerosus

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a comprehensive overview of clinical presentation and emerging evidence supporting a predominantly immune‐mediated pathogenesis characterized by Th1‐skewed inflammation, epithelial dysfunction and progressive fibrosis. Contributory factors including the emerging role for occlusive exposure of susceptible epithelium to urine are ...
Ashley Spencer, Sandra Jerkovic Gulin
wiley   +1 more source

Recirculating bioavailable nicotine metabolite using ascorbic acid: A pragmatic approach for treating nicotine dependence

open access: yesAdvances in Redox Research
Nicotine undergoes metabolism, converting into the oxidized metabolite cotinine, which can persist in the body for several weeks and potentially lead to fatal conditions, such as cancer.
Murugesan Arumugam   +5 more
doaj   +1 more source

An Umbrella Review of Artificial Intelligence Applications in Mental Health Care

open access: yesJournal of Psychiatric and Mental Health Nursing, EarlyView.
ABSTRACT Background Artificial intelligence (AI) is increasingly used in mental health care to address rising demand, workforce shortages and access barriers; however, evidence remains scattered across multiple systematic reviews, limiting synthesis and practical application.
Jonathan Odame   +6 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger   +5 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini   +3 more
wiley   +1 more source

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