Results 141 to 150 of about 3,355,558 (275)

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Targeting Orexin 2 Receptors in Idiopathic Hypersomnia and Narcolepsy: A Randomised Phase 1b Proof‐Of‐Concept Study of Alixorexton

Journal of Sleep Research, EarlyView.
Orexin 2 receptor agonists have demonstrated that targeting the orexin system may address symptoms of central disorders of hypersomnolence. Results of this phase 1 study support the phase 2 clinical evaluation of oral alixorexton in patients with IH, NT2 and NT1.
Ronald R. Grunstein, Brendon J. Yee, Julia L. Chapman, Jian Eu Tai, Sheila Sivam, Craig Hopkinson, Daniel G. Smith, Alexandra Lovett, Shifang Liu, Sergey Yagoda, Bhaskar Rege   +10 more
wiley   +1 more source

Differential Diagnosis Performance of ChatGPT in Oral and Maxillofacial Pathology

Oral Diseases, EarlyView.
ABSTRACT Objective To evaluate ChatGPT (GPT‐5.1) for ranked differential diagnoses in oral and maxillofacial pathology, assess image effects on diagnostic performance and examine output stability across repeated runs. Methods This retrospective diagnostic accuracy study included 160 biopsy‐confirmed cases.
Sohaib Shujaat, Marryam Riaz, Jawaher Mohammed Alsubaie, Aljwhrah Abdulaziz Almuammar, Arun Pillai, Abdulmohsen Alfadley, Ali Anwar Aboalela   +6 more
wiley   +1 more source

Impact of ICD Presence in Patients With Left Ventricular Assist Devices for End‐Stage Heart Failure

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The prognostic relevance of implantable cardioverter defibrillator (ICD) in patients with end‐stage heart failure (HF) with left ventricular assist device (LVAD) remains controversial. Objectives To evaluate the prognostic impact of ongoing use of ICD and associated complications in HF‐patients with LVAD‐implantation.
Nafilah Baridwan, Mustafa Gerçek, Muhammed Gerçek, Michiel Morshuis, Thomas Eitz, René Schramm, Volker Rudolph, Jan F. Gummert, Philipp Sommer, Christian Sohns, Angelika Costard‐Jäckle, Guram Imnadze   +11 more
wiley   +1 more source

A study on the efficacy and tolerability of Chinese traditional medicine using herbal patches in smoking cessation [PDF]

, 2004
Cigarette smoking is a major public health issue in both developed and developing countries. There is estimated to be over a billion smokers in the world today, with almost one third of them living in China.
Wang, Yuzhuo
core  

Altered prefrontal suppression of striatal activity during intrusive images in obsessive‐compulsive disorder

Psychiatry and Clinical Neurosciences, EarlyView.
Background Current models of obsessive‐compulsive disorder (OCD) emphasize dysfunction in frontostriatal circuits that support flexible behavioral control, leading to impulsive and compulsive actions. However, how these disruptions contribute to obsessions and intrusive thoughts remains poorly understood.
Anaïs Vandevelde, Sonia Dollfus, Pierre Gagnepain   +2 more
wiley   +1 more source

Smoking Cessation Strategies Targeting Specific Populations

Tuberculosis and Respiratory Diseases, 2019
Quitting smoking helps smokers maintain their health and extend their lifespan by 10 or more years. Treatment strategies for smoking cessation should be tailored to individual smokers with special needs based on their specific circumstances.
Eun Mi Chun, M.D., Ph.D.
doaj  

Hormone replacement therapy: perspectives from women, medicine and sociology [PDF]

, 1997
Developed on the boundary between medicine and sociology, this thesis develops a critique of the perspectives of these disciplines through analysis of a study of women's perspectives on hormone replacement therapy.
Griffiths, Frances Ellen, Griffiths, F.E.   +1 more
core  

Nicotine Replacement Therapy [PDF]

American Journal of Psychiatry Residents' Journal, 2016
openaire   +1 more source

Factors affecting the efficacy of nonsurgical therapy of peri‐implantitis

Periodontology 2000, EarlyView.
Abstract Objectives and Materials and Methods This article critically reviews the current knowledge on the factors influencing the efficacy of non‐surgical therapy (NST) of peri‐implantitis, taking also advantage of the know‐how from periodontitis management.
Elena Calciolari, Federico Rivara, Nikolaos Donos, Jérôme F. Lasserre, Selena Toma   +4 more
wiley   +1 more source