Results 261 to 270 of about 156,732 (304)
Some of the next articles are maybe not open access.
British Journal of Addiction, 1989
SummaryIn recent years progress in basic neuropsychopharmacology and clinical addiction research have allowed the conclusion that tobacco smoking essentially represents an addiction to nicotine. Parallel to this work, experimental research in biochemistry, physiology and pharmacology has provided detailed descriptions of the structure and function of ...
J, Grenhoff, T H, Svensson
openaire +2 more sources
SummaryIn recent years progress in basic neuropsychopharmacology and clinical addiction research have allowed the conclusion that tobacco smoking essentially represents an addiction to nicotine. Parallel to this work, experimental research in biochemistry, physiology and pharmacology has provided detailed descriptions of the structure and function of ...
J, Grenhoff, T H, Svensson
openaire +2 more sources
Psychopharmacology, 1992
This issue has covered most of the important concerns of nicotine researchers. Inevitably, there are gaps, because the selection of papers could only cover those which had been submitted or were known to be in preparation and about to be submitted. Nevertheless, these articles should serve to stimulate further discussion of and investigation into all ...
openaire +2 more sources
This issue has covered most of the important concerns of nicotine researchers. Inevitably, there are gaps, because the selection of papers could only cover those which had been submitted or were known to be in preparation and about to be submitted. Nevertheless, these articles should serve to stimulate further discussion of and investigation into all ...
openaire +2 more sources
Drug and Therapeutics Bulletin, 2014
Nicotine, an alkaloid derived from the leaves of tobacco plants (Nicotiana tabacum and Nicotiana rustica) is the primary addictive agent in tobacco products.1,2 There are different ways of administering the various products including smoking cigarettes, chewing tobacco, holding moist snuff in the mouth, inhaling dry snuff through the nose, inhaling ...
openaire +2 more sources
Nicotine, an alkaloid derived from the leaves of tobacco plants (Nicotiana tabacum and Nicotiana rustica) is the primary addictive agent in tobacco products.1,2 There are different ways of administering the various products including smoking cigarettes, chewing tobacco, holding moist snuff in the mouth, inhaling dry snuff through the nose, inhaling ...
openaire +2 more sources
1981
Cigarette smoking is one of the most persistent habits known to man; for many years, he has been possessed by the bizarre but irresistible urge to inhale the smoke produced by burning the dried and shredded leaves of Nicotiana tabacum. The alternative methods of administration, sniffing and chewing, lost favor with the introduction of cheap cigarettes ...
R, Kumar, M, Lader
openaire +2 more sources
Cigarette smoking is one of the most persistent habits known to man; for many years, he has been possessed by the bizarre but irresistible urge to inhale the smoke produced by burning the dried and shredded leaves of Nicotiana tabacum. The alternative methods of administration, sniffing and chewing, lost favor with the introduction of cheap cigarettes ...
R, Kumar, M, Lader
openaire +2 more sources
Biochemical and Biophysical Research Communications, 1975
Abstract A sensitive and specific radioimmunoassay of nicotine was developed using antisera raised against 6-(p-aminobenzamido) nicotine coupled to bovine serum albumin. Inhibition studies with various nicotine analogues revealed that the antisera are highly specific for both the N-methylpyrrolidine ring and the pyridine ring of nicotine, and ...
S, Matsukura +6 more
openaire +2 more sources
Abstract A sensitive and specific radioimmunoassay of nicotine was developed using antisera raised against 6-(p-aminobenzamido) nicotine coupled to bovine serum albumin. Inhibition studies with various nicotine analogues revealed that the antisera are highly specific for both the N-methylpyrrolidine ring and the pyridine ring of nicotine, and ...
S, Matsukura +6 more
openaire +2 more sources
Science, 1959
Radioactive nicotine was synthesized by Nicotiana rustica L. which was fed sodium acetate-1-C 14 , sodium acetate-2-C 14 , sodium pyruvate-1-C 14 , or sodium pyruvate-3-C 14 .
T, GRIFFITH, R U, BYERRUM
openaire +2 more sources
Radioactive nicotine was synthesized by Nicotiana rustica L. which was fed sodium acetate-1-C 14 , sodium acetate-2-C 14 , sodium pyruvate-1-C 14 , or sodium pyruvate-3-C 14 .
T, GRIFFITH, R U, BYERRUM
openaire +2 more sources
2017
Nicotine is a psychoactive drug with effects that reinforce tobacco use despite known adverse health consequences. Nicotine dependence can be effectively treated. Family physicians are in an excellent position to promote both smoking cessation and smoking prevention.
openaire +2 more sources
Nicotine is a psychoactive drug with effects that reinforce tobacco use despite known adverse health consequences. Nicotine dependence can be effectively treated. Family physicians are in an excellent position to promote both smoking cessation and smoking prevention.
openaire +2 more sources
Chronopharmacokinetics of nicotine*
Clinical Pharmacology & Therapeutics, 1996For high-clearance drugs such as nicotine, hemodynamic changes throughout the day may be expected to influence the rate of metabolism.To assess the effects of meals and diurnal rhythms on nicotine clearance, an intravenous infusion of nicotine bitartrate was administered for 48 hours to 11 subjects.
J M, Gries, N, Benowitz, D, Verotta
openaire +2 more sources
Nature, 1953
FOLLOWING the demonstration that the amino-acid tryptophane can readily be converted by barley plants into the alkaloid gramine1, the study of the biogenesis of alkaloids carried on here has included investigations into the possibility that nicotine may arise from tryptophane in a manner similar to the formation of nicotinic acid in animals and ...
openaire +2 more sources
FOLLOWING the demonstration that the amino-acid tryptophane can readily be converted by barley plants into the alkaloid gramine1, the study of the biogenesis of alkaloids carried on here has included investigations into the possibility that nicotine may arise from tryptophane in a manner similar to the formation of nicotinic acid in animals and ...
openaire +2 more sources
Structure and gating mechanism of the α7 nicotinic acetylcholine receptor
Cell, 2021Anant Gharpure +2 more
exaly