Results 1 to 10 of about 77,143 (337)
Nicotinic acetylcholine receptors [PDF]
British Journal of Pharmacology, 2018 This themed section of the British Journal of Pharmacology is the product of a conference that focussed on nicotinic ACh receptors (nAChRs) that was held on the Greek island of Crete from 7 to 11 May 2017. ‘Nicotinic acetylcholine receptors 2017’ was the fourth in a series of triennial international meetings that have provided a regular forum for ...
Wonnacott, S +3 more
openaire +6 more sources
Nicotinic acetylcholine receptors and epilepsy
Pharmacological Research, 2023 Despite recent advances in understanding the causes of epilepsy, especially the genetic, comprehending the biological mechanisms that lead to the epileptic phenotype remains difficult. A paradigmatic case is constituted by the epilepsies caused by altered neuronal nicotinic acetylcholine receptors (nAChRs), which exert complex physiological functions ...
Becchetti A. +3 more
openaire +5 more sources
Nicotinic Acetylcholine Receptors in the Respiratory Tract [PDF]
Molecules, 2021 Nicotinic acetylcholine receptors (nAChR) are widely distributed in neuronal and non-neuronal tissues, where they play diverse physiological roles. In this review, we highlight the recent findings regarding the role of nAChR in the respiratory tract with a special focus on the involvement of nAChR in the regulation of multiple processes in health and ...
Hollenhorst, Monika I. +1 more
openaire +4 more sources
Nicotinic acetylcholine receptor mutations [PDF]
Epilepsia, 2010 SummaryAutosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is characterized by clusters of brief motor seizures. This rare syndrome is caused by mutations in at least two subunit genes of the neuronal nicotinic acetylcholine receptor (nAChR). Some of these mutations seem to increase the risk for additional neurologic symptoms.
Sunao Kaneko +2 more
openaire +2 more sources
Characterization of nicotine acetylcholine receptor subunits in the cockroach Periplaneta americana mushroom bodies reveals a strong expression of β1 subunit: involvement in nicotine-induced currents [PDF]
, 2016 Nicotinic acetylcholine receptors are ligand-gated ion channels expressed in many insect structures, such as mushroom bodies, in which they play a central role.
E. Taillebois, S.H. Thany
core +3 more sources
Alzheimer’s Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts [PDF]
, 2019 Biological membranes show lateral and transverse asymmetric lipid distribution. Cholesterol (Chol) localizes in both hemilayers, but in the external one it is mostly condensed in lipid-ordered microdomains (raft domains), together with saturated ...
Antollini, Silvia Susana +1 more
core +1 more source
Commentary: Nicotinic acetylcholine receptor α9 and α10 subunits are expressed in the brain of mice [PDF]
, 2018 Fil: Morley, Barbara J.. Boys Town National Research Hospita; Estados UnidosFil: Whiteaker, Paul. Barrow Neurological Institute; Estados UnidosFil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas.
Elgoyhen, Ana Belen +2 more
core +1 more source
Activation of a nicotinic acetylcholine receptor
Biophysical Journal, 1984 We studied activation of the nicotinic acetylcholine (ACh) receptor on cells of a mouse clonal muscle cell line (BC3H1). We analyzed single-channel currents through outside-out patches elicited with various concentrations of acetylcholine (ACh), carbamylcholine (Carb) and suberyldicholine (Sub).
Joe Henry Steinbach, Steven M. Sine
openaire +2 more sources
Alpha9 nicotinic acetylcholine receptors and the treatment of pain [PDF]
, 2009 Chronic pain is a vexing worldwide problem that causes substantial disability and consumes significant medical resources. Although there are numerous analgesic medications, these work through a small set of molecular mechanisms.
Absalom, Nathan +4 more
core +1 more source
Palmitoylation of Nicotinic Acetylcholine Receptors [PDF]
Journal of Molecular Neuroscience, 2009 It is well established that nicotinic acetylcholine receptors (nAChRs) undergo a number of different posttranslational modifications, such as disulfide bond formation, glycosylation, and phosphorylation. Recently, our laboratory has developed more sensitive assays of protein palmitoylation that have allowed us and others to detect the palmitoylation of
M. P. Blanton +6 more
openaire +3 more sources