Results 21 to 30 of about 1,317,031 (279)
Vagus nerve stimulation is a potential treatment for ischemic stroke
Neural Regeneration Research, 2023 Microglia are the brain’s primary innate immune cells, and they are activated and affect pro-inflammatory phenotype or regulatory phenotype after ischemic stroke.
Yi-Lin Liu +4 more
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Understanding of nicotinic acetylcholine receptors [PDF]
Acta Pharmacologica Sinica, 2009 Cigarette smoking is a major public health problem and has been identified as the second-most prevalent cause of death in the world. China, a country with a population of 1.3 billion, is the world's largest producer and consumer of tobacco. It estimates that there are 0.35 billion cigarette smokers in China, which bears a large proportion of the deaths
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Embedded Cholesterol in the Nicotinic Acetylcholine Receptor [PDF]
Biophysical Journal, 2008 The nicotinic acetylcholine receptor (nAChR) is a cation-selective channel central to both neuronal and muscular processes and is considered the prototype for ligand-gated ion channels, motivating a structural determination effort that spanned several decades [Unwin N (2005) Refined structure of the nicotinic acetylcholine receptor
Brannigan, Grace +4 more
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Differing time dependencies of object recognition memory impairments produced by nicotinic and muscarinic cholinergic antagonism in perirhinal cortex [PDF]
, 2011 The roles of muscarinic and nicotinic cholinergic receptors in perirhinal cortex in object recognition memory were compared. Rats' discrimination of a novel object preference test (NOP) test was measured after either systemic or local infusion into the ...
Warburton, E Clea +20 more
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Neuronal and Extraneuronal Nicotinic Acetylcholine Receptors [PDF]
Current Neuropharmacology, 2018 Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a super-family of Cysloop ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other cholinergic ligands. These receptors are also the targets of drugs such as nicotine (the main addictive agent delivered by cigarette smoke) and are involved in a variety of ...
Zoli Michele +3 more
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Single-Molecule Studies of Ion Channels Expressing Unnatural Amino Acids [PDF]
, 2011 The nicotinic acetylcholine receptors are pentameric ligand-gated ion channels that mediate fast synaptic transmission in the brain and peripheral nervous system.
Shanata, Jai Anand Pattur
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Cell Reports, 2016 Monoamine and acetylcholine neurotransmitters from the autonomic nervous system (ANS) regulate insulin secretion in pancreatic islets. The molecular mechanisms controlling neurotransmitter signaling in islet β cells and their impact on diabetes ...
Elvira Ganic +14 more
doaj +1 more source
Loop B is a major structural component of the 5-HT3 receptor [PDF]
, 2008 The 5-HT3 receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence of six peptide loops (A-F).
Thompson, Andrew J. +9 more
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Nicotinic acetylcholine receptors and cancer
Biomedical Reports, 2016 Nicotine, the primary addictive constituent of cigarettes, is believed to contribute to cancer promotion and progression through the activation of nicotinic acetylcholine receptors (nAChRs), which are membrane ligand-gated cation channels. nAChRs activation can be triggered by the neurotransmitter Ach, or certain other biological compounds, such as ...
DANG, NINGNING +2 more
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Neuronal nicotinic receptors as new targets foramphetamine-induced oxidative damage and neurotoxicity [PDF]
, 2011 Amphetamine derivatives such as methamphetamine (METH) and 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) are drugs widely abused in a recreational context.
Pubill Sánchez, David +7 more
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