Journal of Peptide Science, Volume 31, Issue 6, June 2025.This study cyclized conotoxin Vc1.1 using polyethylene glycol (PEG) linkers of different lengths and demonstrates that linker length modulates the peptide's helicity, thereby influencing its biological activity and stability. ABSTRACT α‐Conotoxin Vc1.1 is a disulfide‐rich peptide and a promising drug candidate for treating neuropathic and chronic pain.
Yuhui Zhang +4 more
wiley +1 more source
Journal of Pharmacological Sciences, 2008 Acetylcholine (ACh) is a phylogenetically ancient molecule involved in cell-to-cell signaling in almost all life-forms on earth. Cholinergic components, including ACh, choline acetyltransferase, acetylcholinesterase, and muscarinic and nicotinic ACh ...
Significance Koichiro Kawashima +1 more
doaj
Monoclonal antibodies directed against the neurotransmitter binding site of nicotinic acetylcholine receptor [PDF]
, 1980 Richard W. James +3 more
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Cyto‐Genotoxic Assessment of Sulfoxaflor in Allium cepa Root Cells and DNA Docking Studies
Microscopy Research and Technique, Volume 88, Issue 5, Page 1521-1533, May 2025.Cyto‐genotoxic Assessment of Sulfoxaflor in Allium cepa Root Cells and DNA Docking Studies. ABSTRACT Sulfoxaflor (SFX) is an insecticide that is commonly used for the control of sap‐feeding insects. Since SFX is extensively applied globally, it has been implicated in the substantial induction of environmental toxicity.
Recep Liman +7 more
wiley +1 more source
Three-dimensional structure of the nicotinic acetylcholine receptor and location of the major associated 43-kD cytoskeletal protein, determined at 22 A by low dose electron microscopy and x-ray diffraction to 12.5 A [published erratum appears in J Cell Biol 1989 Oct;109(4 Pt 1):1185] [PDF]
, 1989 Alok K. Mitra
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Discovery and biological characterization of a novel mesoionic insecticide fenmezoditiaz
Pest Management Science, Volume 81, Issue 5, Page 2535-2552, May 2025.Acetylcholine binding protein (AChBP) from the sea slug Aplysia californica was modified using site‐directed mutagenesis to create an insect‐like binding site enabling structure‐based compound design. Fenmezoditiaz is a systemic insecticide with a broad spectrum, lack of cross‐resistance and an additional tool for integrated pest management and ...
Huazhang Huang +8 more
wiley +1 more source
Recent innovations in crop protection research
Pest Management Science, Volume 81, Issue 5, Page 2406-2418, May 2025.This review summarizes the latest innovations presented at the 15th IUPAC International Congress on Crop Protection Chemistry in New Delhi in 2023. New products and approaches to control insects, nematodes, diseases, and weeds are discussed, as well as recent advancements in crop enhancement and green pest management research.
Peter Maienfisch, Karsten Koerber
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Triphenylmethylphosphonium is an ion channel ligand of the nicotinic acetylcholine receptor.
, 1982 L Lauffer, Ferdinand Hucho
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Three conductance classes of nicotinic acetylcholine receptors are expressed in developing amphibian skeletal muscle [PDF]
, 1989 JL Owens, R Kullberg
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Agricultural and Forest Entomology, Volume 27, Issue 2, Page 137-147, May 2025.Abstract 1. The invasive hemlock woolly adelgid (HWA), Adelges tsugae (Annand) (Hemiptera: Adelgidae), has spread throughout most of the range of eastern hemlock, Tsuga canandensis (L.), and the entire range of Carolina hemlock, Tsuga caroliniana (Engelman), in the United States. 2. Integrated pest management (IPM) of HWA combines chemical applications
Ashleigh P. Hillen +6 more
wiley +1 more source