Results 151 to 160 of about 1,317,031 (279)

TMEM16A Ca2+‐activated Cl− channel: Functional interactions with cytoskeletal and membrane‐associated proteins

The Journal of Physiology, EarlyView.
Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura, Rubii Kondo, Yoshiaki Suzuki, Yuji Imaizumi, Aya Yamamura   +4 more
wiley   +1 more source

Pharmacological studies on acetylcholine and other transmitter receptors from invertebrate muscle and central neurones

, 1988
Muscle tension recordings were made from earthworm body wall muscle and the action of acetylcholine, cholinomimtics and cholinolytics examined. The effect of cholinergic agents on muscle twitches induced following field stimulation was also investigated.
Hassoni, Abdul-Nabi Atya, Hassoni, A.A
core   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Stac2 genetic deletion alters mouse chromaffin cells’ CaV channel composition, increases membrane excitability and reduces vesicle exocytosis

The Journal of Physiology, EarlyView.
Abstract figure legend Stac2 adaptor protein is expressed in neurons and endocrine cells. Using a global Stac2 knockout mouse model here we investigated the role of endogenous Stac2 in adrenal gland mouse chromaffin cell (MCC) excitability and catecholamine vesicle exocytosis.
Stefanie M. Geisler, Noelia Jacobo‐Piqueras, Tamara Theiner, Ryoichi S. Taguchi, Laura E. Häfele, Marta Campiglio, Petronel Tuluc   +6 more
wiley   +1 more source

Diabetic Autonomic Neuropathy and Impaired Inflammatory Reflex

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
The cholinergic anti‐inflammatory pathway under normal and diabetic conditions. In the normal state, vagal activation through nicotinic acetylcholine receptors helps regulate immune responses and suppress excessive inflammation. In diabetes, impaired autonomic function and dysregulated cholinergic signalling weaken this anti‐inflammatory pathway ...
Narges Dastmalchi, Mohammad Amin Doustvandi, Reza Rahbarghazi, Khalil Hajiasgharzadeh   +3 more
wiley   +1 more source

Individual Differences in Sleep Quality: Exploring the Impact of Temperament on Sleep Through Anxiety and Depression

Personality and Mental Health, Volume 20, Issue 4, November 2026.
ABSTRACT According to the functional ensemble of temperament (FET) model, individual differences in temperament arise from the balance of neurotransmitter systems also crucial for regulating circadian rhythms and sleep, suggesting a strong neurobiological link between temperament and sleep behavior.
Stefano Lasaponara, Angelica Scuderi, Elisa Pellegrini, Ludovica Annarumma, Valentina Piga, Sara Lo Presti, Maurizio Gorgoni   +6 more
wiley   +1 more source

Modulation of cholinergic synaptic transmission in an identified locust sensory pathway [PDF]

, 2000
The monosynaptic connection between the locust forewing stretch receptor (fSR) and the first basalar motoneuron (BAl) is part of a sensory pathway involved in flight.
Judge, Sarah Jane
core  

Anatomopathological and toxicological analysis of a dog poisoned with methomyl

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A dog with suspected poisoning was submitted for postmortem examination. Generalised visceral congestion was observed in the abdominal cavity, with the liver, kidneys and gastrointestinal tract most severely affected. However, there was no macroscopic evidence of granular material in the gastric contents.
André Valle de Bairros, Fernanda Ziegler Reginato Donadel, Gustavo Andrade Ugalde, Rafael Castanho Chaves, Alexandre Vargas Schwarzbold, Rafael Almeida Fighera   +5 more
wiley   +1 more source

Snus, nicotine pouches and cardiovascular disease: Evidence, mechanisms, and the challenge of novel nicotine products

Journal of Internal Medicine, Volume 300, Issue 5, Page 541-552, November 2026.
Abstract Conventional Swedish snus is used by millions in Scandinavia and increasingly worldwide, yet its cardiovascular effects remain poorly characterized. The emergence of nicotine pouches—commonly referred to as ‘white snus’ in Sweden—that deliver comparable nicotine without tobacco constituents adds complexity to a heterogeneous landscape and ...
Magnus Olsson, Hanne Tønnesen, Jakob Hedberg, Johan Sundström, Eva Nordendahl, Björn Klinge, Michael Fored, Cecilia Magnusson, Daniel Jönsson, Peter Persson, Aron Naimi‐Akbar   +10 more
wiley   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source