Results 131 to 140 of about 70,011 (259)

Sequencing of rabies binding region on nicotinic acteylcholine receptor alpha subunits in four host species [PDF]

, 2013
• Rabies virus is known to bind to nicotinic acetylcholine receptors (nAchR) • The virus is known to bind to alpha 1 subunits nAchR • The virus binding region has been characterized in alpha 1 subunits of these receptors • Little research has been ...
Barnard, Karen
core  

Pain‐Related Smoking Expectancies Across Tobacco Product Use Patterns, Including Heated Tobacco Products: Psychometric Validation of the Japanese Pain and Smoking Inventory

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
The newly validated Japanese Pain and Smoking Inventory (PSI) demonstrates that higher pain‐related smoking expectancies predict greater pain intensity and disability. Among tobacco use patterns, dual users exhibit the highest expectancies, while switchers show the lowest scores.
Keiko Yamada, Takashi Kimura, Naoki Mizunuma, Takahiro Tabuchi   +3 more
wiley   +1 more source

Protease effects on the structure of acetylcholine receptor membranes from Torpedo californica. [PDF]

, 1980
Protease digestion of acetylcholine receptor-rich membranes derived from Torpedo californica electroplaques by homogenization and isopycnic centrifugation results in degradation of all receptor subunits without any significant effect on the appearance in
Heuser, JE, Klymkowsky, MW, Stroud, RM
core   +1 more source

Combined Inhibition of TRPM4/NMDA Receptor Complex and Extrasynaptic NMDA Receptors Is Candidate Therapeutic Target for Suppression of Epileptic Seizures and Improvement of Cognitive Impairments

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Cognitive impairments are important therapeutic targets in epilepsy medication; however, effective pharmacological treatments for epilepsy patients with comorbid cognitive impairment have not been established. Effects of chronic administration of MK‐801 (noncompetitive NMDA receptor inhibitor), memantine (low‐affinity extrasynaptic‐NMDA ...
Motohiro Okada, Ruri Okubo, Tomoka Oka, Eishi Motomura   +3 more
wiley   +1 more source

Co‐pathologies and biological processes beyond amyloid‐beta and tau in people with Alzheimer's disease: Evidence from clinical cohort studies

Journal of Internal Medicine, Volume 299, Issue 6, Page 694-710, June 2026.
Abstract Alzheimer's disease (AD) is neuropathologically defined by amyloid‐beta (Aβ) plaques and tau neurofibrillary tangles. However, co‐pathologies and other pathobiological processes are involved in the pathogenesis of AD, contributing to neurodegeneration and clinical symptoms.
Daniel Ferreira, Tomasz Chmiela, Maria Eriksdotter, Clifford R. Jack Jr., Grégoria Kalpouzos, Anna Marseglia, Patrizia Mecocci, Agneta Nordberg, Dorota Religa, Eric Westman   +9 more
wiley   +1 more source

Tuft cells trigger neurogenic inflammation in the urethra

Cell Reports
Summary: Cholinergic urethral tuft cells (UTCs) are regarded as sentinels of microbial products in the urogenital tract, initiating reflex micturition as a protective mechanism.
Patricia Schmidt, Uwe Pfeil, Mahmoud Lafee, Swantje Petersen, Alexander Perniss, Maryam Keshavarz, Debajyoti Das, Amanda Wyatt, Ulrich Boehm, Burkhard Schütz, Wolfgang Kummer, Klaus Deckmann   +11 more
doaj   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

Note for Male Smokers: The Healthy Eating Index Associated With the Risk of Subclinical Myocardial Injury

Clinical Cardiology, Volume 49, Issue 5, May 2026.
Flow chart of the study population. ABSTRACT Objectives To investigate the associations of the healthy eating index (HEI) and subclinical myocardial injury (SCMI) in different smoking statuses (current smokers, former smokers, and never smokers) based on the National Health and Nutrition Examination Survey (NHANES) III.
Zhi‐jin Li, Bin‐gui Li
wiley   +1 more source

Homoisoflavonoids—From Natural Specificity and Biosynthesis to Precision Health‐Promoting Mechanisms

Food Frontiers, Volume 7, Issue 3, May 2026.
Homoisoflavonoids are rare flavonoids with a unique bi‐aromatic oxygen‐heterocyclic structure. This review synthesizes their structure–activity relationships in anti‐inflammatory, hypoglycemic, and anticancer contexts. By highlighting their specific natural distribution and outlining biosynthetic pathways, it provides a conceptual framework and ...
Jing Zhang, Han Chen, Jinping Si, Zhigang Han, Xinfeng Zhang   +4 more
wiley   +1 more source

The Role of Nootropic Supplements in Sports: Enhancing Cognitive and Physical Performance Simultaneously

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
The review examines the nootropic effects of substances used in sports through their impact on neurotransmission, neuroendocrine control, energy production, synaptic plasticity, and neurovascular connections. The four key neurotransmitters dopamine, acetylcholine, serotonin, and GABA function to control motivation, attention, fatigue perception, and ...
Zheng Yi
wiley   +1 more source