Results 141 to 150 of about 116,303 (277)

Pan-cancer expression, methylation, and prognostic significance of α7 nicotinic acetylcholine receptor in tumor immunology. [PDF]

Biochem Biophys Rep
Bai X, Ma T, Shi L, Wang P, Zhao D, Long J, Hai Y, You Y, Zhao R, Ma L.   +9 more
europepmc   +1 more source

A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX.

Neuron, 1990
S. Couturier, D. Bertrand, J. Matter, Maria-Clemencia Hernandez, S. Bertrand, N. Millar, S. Valera, T. Barkas, M. Ballivet   +8 more
semanticscholar   +1 more source

Restoring Septohippocampal Cholinergic Signaling Rescues Surgery‐Induced Neurogenesis and Memory Deficits in Aged Mice

Aging Cell, Volume 25, Issue 6, June 2026.
Surgery‐induced MS/vDB → DG cholinergic decline impairs hippocampal neurogenesis and memory in aged mice; galantamine‐mediated cholinergic potentiation or sustained chemogenetic activation rescues these deficits, highlighting therapeutic potential for POCD.
Lei Lei, Qingsheng Meng, Xiaoyu Hu, Jinjin Yang, Ni Du, Songxue Su, Kenji Hashimoto, Jing Cao, Jian‐jun Yang   +8 more
wiley   +1 more source

Novel Nicotinic Acetylcholine Receptor Inhibitors Derived from Oleoylcholine Analogs. [PDF]

Acta Naturae
Vladykina MV, Kokaeva IS, Kasheverov IE, Gretskaya NM, Zinchenko GN, Tsetlin VI, Utkin YN, Bezuglov VV, Shelukhina IV.   +8 more
europepmc   +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, Volume 121, Issue 6, Page 1580-1593, June 2026.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann   +2 more
wiley   +1 more source

Alpha7 nicotinic acetylcholine receptor activation attenuates allergic airway inflammation and is associated with heme oxygenase-1 induction. [PDF]

Front Immunol
Iriki J, Fukahori S, Obase Y, Nakamura Y, Umene R, Wu CH, Yamada Y, Takemoto S, Takazono T, Sakamoto N, Fukushima C, Nishino T, Mukae H, Inoue T.   +13 more
europepmc   +1 more source

The phenolic monoterpenoid carvacrol inhibits the binding of nicotine to the housefly nicotinic acetylcholine receptor.

Pest Management Science, 2013
F. Tong, A. Gross, M. Dolan, J. Coats
semanticscholar   +1 more source

tVNS Mitigates Neuroinflammation and Nociception in a Rodent LPS Endotoxemia Model

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
Experimental design and key findings. Four groups (Control+Sham, Control+tVNS, LPS+Sham, LPS+tVNS; n = 7 each) underwent serum ELISA, brain Western blot, and behavioral testing. tVNS altered serum Haptoglobin, IL‐6, CGRP1, and VE‐Cadherin levels, reversed LPS‐induced increases in brain IL‐1β, HMGB1, Haptoglobin, PAR‐2, and CGRP, and alleviated LPS ...
Kerem Atalar, Ece Alim, Aysen Calikusu, Elif Gulcicek Abbasoglu Topa, Hale Gok Dagidir, Meltem Bahcelioglu, Neslihan Bukan, Fusun Erten, Kazım Sahin, Saadet Özen Akarca Dizakar, Hayrunnisa Bolay   +10 more
wiley   +1 more source

Discovery and mechanism of negative allosteric modulation of the α7 nicotinic acetylcholine receptor by nanobodies. [PDF]

Proc Natl Acad Sci U S A
Barilone N, Vangelatou M, Marouf FZ, Dejean de la Bâtie G, Li Q, Lafaye P, Aymé G, Corringer PJ, Prevost MS.   +8 more
europepmc   +1 more source

Correction: Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2. [PDF]

Sci Rep
Yin Y, Wang Y, Gao D, Ye J, Wang X, Fang L, Wu D, Pi G, Lu C, Zhou XW, Yang Y, Wang JZ.   +11 more
europepmc   +1 more source