Results 171 to 180 of about 76,692 (268)

The quest for the best target genes for RNAi‐mediated pest control

open access: yesInsect Molecular Biology, Volume 34, Issue 4, Page 505-517, August 2025.
A major challenge for RNAi mediated pest control is the identification of the most effective RNAi target genes from the pool of ~37% of all genes that are essential. Effective RNAi target genes are predominantly highly conserved genes serving basic cellular functions such as protein degradation.
Doga Cedden, Gregor Bucher
wiley   +1 more source

Enteric neuropathy and the vagus nerve: Therapeutic implications

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley   +1 more source

Effects of sugammadex on heart rate variability in anesthetized male rats

open access: yesPhysiological Reports, Volume 13, Issue 15, August 2025.
Abstract The administration of sugammadex has been associated with bradycardia and rarely asystole; however, the underlying mechanisms remain unclear. We examined heart rate variability (HRV) as an index of autonomic nervous system activity and investigated the effects of sugammadex on HRV in α‐chloralose and urethane anesthetized male rats.
Mika Nishikawa   +4 more
wiley   +1 more source

Molecular insights into the α6β4 nicotinic acetylcholine receptor function and ligand recognition. [PDF]

open access: yesNat Commun
Su J   +10 more
europepmc   +1 more source

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