Results 171 to 180 of about 79,918 (320)
Activation of Nicotinic Acetylcholine Receptors Augments Calcium Channel-mediated Exocytosis in Rat Pheochromocytoma (PC12) Cells [PDF]
Amy B. Harkins, Aaron P. Fox
openalex +1 more source
A selective 7 nicotinic acetylcholine receptor agonist, PNU-282987, attenuates ILC2s activation and Alternaria induced airway inflammation [PDF]
Fang Yuan +8 more
openalex +1 more source
The diversity and abundance of the gut microbiome in rats were significantly disrupted following post‐anesthesia sleep disturbance. Lactobacillales and Bifidobacterium yogurt supplementations increased sleep quality considerably and the abundance of beneficial bacteria, while reducing wakefulness and wake‐related metabolites in the gut.
Rui‐zhi Yang +7 more
wiley +1 more source
Spirocyclic Diamine Scaffolds for Medicinal Chemistry
Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel +3 more
wiley +1 more source
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U +6 more
wiley +1 more source
Comparison of Conformations and Interactions with Nicotinic Acetylcholine Receptors for E. coli-Produced and Synthetic Three-Finger Protein SLURP-1 [PDF]
Vladimir Kost +11 more
openalex +1 more source
Nicotinic acetylcholine receptors
Jean-Pierre Changeux +1 more
openaire +1 more source
Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar +2 more
wiley +1 more source
Characterisation of an unusual nicotinic acetylcholine receptor subtype preferentially sensitive to biogenic amines. [PDF]
Mitchell EL +6 more
europepmc +1 more source

