Results 171 to 180 of about 79,918 (320)

A selective 7 nicotinic acetylcholine receptor agonist, PNU-282987, attenuates ILC2s activation and Alternaria induced airway inflammation [PDF]

open access: green, 2020
Fang Yuan   +8 more
openalex   +1 more source

Effect of Targeted Probiotics on Anesthesia‐Induced Sleep Disturbances via Modulating the Gut Microbiome and Metabolites

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
The diversity and abundance of the gut microbiome in rats were significantly disrupted following post‐anesthesia sleep disturbance. Lactobacillales and Bifidobacterium yogurt supplementations increased sleep quality considerably and the abundance of beneficial bacteria, while reducing wakefulness and wake‐related metabolites in the gut.
Rui‐zhi Yang   +7 more
wiley   +1 more source

Spirocyclic Diamine Scaffolds for Medicinal Chemistry

open access: yesHelvetica Chimica Acta, Volume 109, Issue 1, January 2026.
Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel   +3 more
wiley   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

open access: yesJournal of Applied Toxicology, Volume 46, Issue 1, Page 179-197, January 2026.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U   +6 more
wiley   +1 more source

Comparison of Conformations and Interactions with Nicotinic Acetylcholine Receptors for E. coli-Produced and Synthetic Three-Finger Protein SLURP-1 [PDF]

open access: gold, 2023
Vladimir Kost   +11 more
openalex   +1 more source

Nicotinic acetylcholine receptors

open access: yesScholarpedia, 2008
Jean-Pierre Changeux   +1 more
openaire   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar   +2 more
wiley   +1 more source

Characterisation of an unusual nicotinic acetylcholine receptor subtype preferentially sensitive to biogenic amines. [PDF]

open access: yesCommun Biol
Mitchell EL   +6 more
europepmc   +1 more source

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