Results 201 to 210 of about 77,143 (337)
Abstract Background and aims There is growing evidence that tobacco smoking causes depression, but it is unclear which constituents of tobacco smoke (e.g. nicotine, carbon monoxide) may be responsible. We used Mendelian randomisation (MR) to measure the independent effect of nicotine on depression, by adjusting the effect of circulating nicotine ...
Chloe Burke+7 more
wiley +1 more source
Functional expression of nicotinic acetylcholine receptors containing rat α7 subunits in human SH‐SY5Y neuroblastoma cells [PDF]
Elzbieta Puchacz+3 more
openalex +1 more source
Background and Purpose Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned.
Sara Traserra+4 more
wiley +1 more source
Bacterial purine metabolism modulates C. elegans development and stress tolerance via DAF‐16
Purine metabolism is crucial for cellular function and is a conserved metabolic network from prokaryotes to humans, but remains poorly understood in metazoan. To investigate the impact of dietary components on purine metabolism and animal growth, we screened the effects of an Escherichia coli single‐gene deletion library on the growth of the nematode ...
Min Feng+3 more
wiley +1 more source
Nicotinic acetylcholine receptors in porcine hypophyseal intermediate lobe cells. [PDF]
Zhongwei Zhang, P. Feltz
openalex +1 more source
A trace amine beta‐phenylethylamine is anxiolytic and reduces brain acetylcholine at 12 μg/L, but elevates anxiety and cortisol levels at 1000 μg/L. Acute tryptamine at 7 mg/L is anxiogenic, reduces shoaling and social interaction, but elevates brain acetylcholine and cortisol levels. Acute tyramine at 15 μg/L, and octopamine at 125, 500, and 1500 μg/L,
Thalia M. Quintanilha+10 more
wiley +1 more source
Two residues determine nicotinic acetylcholine receptor requirement for RIC-3. [PDF]
Noonan JD, Beech RN.
europepmc +1 more source
ABSTRACT Background Chronic temporomandibular disorder (TMD) pain significantly impairs quality of life and lacks universally effective treatments. Antidepressants, traditionally used for mood disorders, have shown potential in managing chronic pain conditions.
Takara Dei+5 more
wiley +1 more source