Results 21 to 30 of about 145,182 (364)
Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity
Nature Communications, 2016 Allergic asthma is a complex and chronic inflammatory disorder that is associated with airway hyperreactivity (AHR) and driven by Th2 cytokine secretion.
Lauriane Galle-Treger +7 more
semanticscholar +1 more source
Expression of the α7 nicotinic acetylcholine receptor in human lung cells
Respiratory Research, 2005 Background We and others have shown that one of the mechanisms of growth regulation of small cell lung cancer cell lines and cultured pulmonary neuroendocrine cells is by the binding of agonists to the α7 neuronal nicotinic acetylcholine receptor.
Schuller Hildegard M +2 more
doaj +1 more source
Arachidonic Acid as a Possible Negative Feedback Inhibitor of Nicotinic Acetylcholine Receptors on Neurons [PDF]
, 1995 Neuronal acetylcholine receptors, being highly permeable to calcium, are likely to regulate calcium-dependent events in neurons. Arachidonic acid is a membrane-permeant second messenger that can be released from membrane phospholipids by phospholipases ...
Berg, Darwin K. +3 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2015 Significance In this study we take advantage of a recently described chimera of the α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding protein (AChBP), termed α7-AChBP.
R. Spurny +11 more
semanticscholar +1 more source
The distribution of charged amino acid residues and the Ca(2+) permeability of nicotinic acetylcholine receptors: a predictive model [PDF]
, 2017 Nicotinic acetylcholine receptors (nAChRs) are cation-selective ligand-gated ion channels exhibiting variable Ca(2+) permeability depending on their subunit composition.
Fucile, Sergio
core +1 more source
Understanding of nicotinic acetylcholine receptors [PDF]
Acta Pharmacologica Sinica, 2009 Cigarette smoking is a major public health problem and has been identified as the second-most prevalent cause of death in the world. China, a country with a population of 1.3 billion, is the world's largest producer and consumer of tobacco. It estimates that there are 0.35 billion cigarette smokers in China, which bears a large proportion of the deaths
openaire +2 more sources
Cell Reports, 2016 Monoamine and acetylcholine neurotransmitters from the autonomic nervous system (ANS) regulate insulin secretion in pancreatic islets. The molecular mechanisms controlling neurotransmitter signaling in islet β cells and their impact on diabetes ...
Elvira Ganic +14 more
doaj +1 more source
Data in Brief, 2020 This manuscript is a companion paper to Ulleryd M.U. et al., “Stimulation of alpha 7 nicotinic acetylcholine receptor (α7nAChR) inhibits atherosclerosis via immunomodulatory effects on myeloid cells” Atherosclerosis, 2019 [1]. Data shown here include RNA
Marcus A. Ulleryd +10 more
doaj +1 more source
Neural Regeneration Research, 2016 Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction.
Hai-peng Huang, Hong Pan, Hong-feng Wang
doaj +1 more source
The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]
, 2009 Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen +2 more
core +1 more source