ABSTRACT The α7 nicotinic acetylcholine receptor (α7 nAChR) has emerged as a key target for treating cognitive dysfunction in neurological disorders such as Alzheimer's disease (AD) and schizophrenia. α7 nAChRs play essential roles in neurotransmission, neuroinflammation and synaptic plasticity, not only in neurons but also in glial cells, where they ...
Janus H. Magnussen
wiley +1 more source
Significance of nicotine and nicotinic acetylcholine receptors in Parkinson's disease. [PDF]
Lin X, Li Q, Pu M, Dong H, Zhang Q.
europepmc +1 more source
d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor. [PDF]
Steen E. Pedersen, Jonathan B. Cohen
openalex +1 more source
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi+6 more
wiley +1 more source
The Role of α7-Nicotinic Acetylcholine Receptors in the Pathophysiology and Treatment of Parkinson's Disease. [PDF]
ElNebrisi E, Lozon Y, Oz M.
europepmc +1 more source
Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium. [PDF]
Sakata S, Ono F.
europepmc +1 more source
Induction of Na+/K+‐ATPase activity by long‐term stimulation of nicotinic acetylcholine receptors in C2C12 myotubes [PDF]
Robert H. Henning+3 more
openalex +1 more source
Nicotinic acetylcholine receptors in human genetic disease
C. Schaaf
semanticscholar +1 more source
G protein‐coupled receptor‐mediated autophagy in health and disease
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan+2 more
wiley +1 more source
α7 nicotinic acetylcholine receptors regulate radial glia fate in the developing human cortex. [PDF]
Mukhtar T+20 more
europepmc +1 more source