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The Journal of Physiology, EarlyView.Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li +19 more
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Analytical Science Advances, Volume 7, Issue 1, June 2026.ABSTRACT This study investigated the prevalence of electronic smoking device (ESD) use and its associated behavioural and chemical risks among university students in Bahia, Brazil. A cross‐sectional survey was conducted with 355 students from public and private institutions through an online questionnaire between April and May 2023. Among participants,
Eduard F. Valenzuela +7 more
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Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management
Journal of Applied Toxicology, Volume 46, Issue 6, Page 1856-1870, June 2026.ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz +3 more
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Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.The odds ratios and corresponding 95% confidence intervals for suicide death by 5‐HTTLPR S allele, in main and subgroup analyses. Statistical significance is indicated. ABSTRACT Introduction More than 720 000 individuals die by suicide annually worldwide, making it a major public health concern and a leading cause of death among young people ...
Shohei Okada +11 more
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Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT Cognitive impairments are important therapeutic targets in epilepsy medication; however, effective pharmacological treatments for epilepsy patients with comorbid cognitive impairment have not been established. Effects of chronic administration of MK‐801 (noncompetitive NMDA receptor inhibitor), memantine (low‐affinity extrasynaptic‐NMDA ...
Motohiro Okada +3 more
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Journal of Sustainable Agriculture and Environment, Volume 5, Issue 2, June 2026.ABSTRACT The overuse of synthetic pesticides in agriculture has raised significant environmental and health concerns. Biopesticides have emerged as viable, environmentally compatible alternatives. However, recent comprehensive reviews integrating all biopesticide categories and emphasizing their contribution to synthetic‐pesticide‐free and health‐safe ...
Molalign Assefa +5 more
wiley +1 more source
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Nicotinic acid: recent developments
Current Opinion in Cardiology, 2008To review the recent progress in niacin research that is made in two major areas: new preparations to decrease flushing and niacin's mechanism of action.Flushing, an adverse effect of niacin, results from GPR109A-mediated production of prostaglandin D2 and E2 in Langerhans' cells which act on DP1 and EP2/4 receptors in dermal capillaries causing their ...
Vaijinath S, Kamanna +2 more
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Cholesteremia and Nicotinic Acid
Archives of Internal Medicine, 1957Introduction Arteriosclerosis is by far the leading cause of heart disease in old age, 8 although it does not spare the young. 10,13,17 It also offers an increasing problem in psychogeriatrics, largely because of its progressive incidence with senescence and because of increasing longevity.
P O, O'REILLY, M, DEMAY, K, KOTLOWSKI
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