Results 211 to 220 of about 5,143,045 (401)

ElixirSeeker: A Machine Learning Framework Utilizing Fusion Molecular Fingerprints for the Discovery of Lifespan‐Extending Compounds

Aging Cell, EarlyView.
ElixirSeeker is a machine learning architecture based on a phenotype‐driven drug discovery approach to screen lifespan‐extending compounds. By integrating molecular fingerprints, ElixirSeeker could maximize feature capture of lifespan‐extending compounds.
Yan Pan, Hongxia Cai, Fang Ye, Wentao Xu, Zhihang Huang, Jingyuan Zhu, Yiwen Gong, Yutong Li, Anastasia Ngozi Ezemaduka, Shan Gao, Shunqi Liu, Guojun Li, Hao Li, Jing Yang, Junyu Ning, Bo Xian   +15 more
wiley   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Protective role of Angiogenin in muscle regeneration in amyotrophic lateral sclerosis: Diagnostic and therapeutic implications

Brain Pathology, EarlyView.
Elevated angiogenin levels in skeletal muscle are linked to slower disease progression, enhanced regeneration, and vascularization through satellite‐endothelial interaction during myogenesis in ALS. Angiogenin and its tiRNAs may serve as prognostic markers and therapeutic targets for ALS.
Paola Fabbrizio, Sharada Baindoor, Cassandra Margotta, Junyi Su, Elena P. Morrissey, Ina Woods, Marion C. Hogg, Sara Vianello, Morten T. Venø, Jørgen Kjems, Gianni Sorarù, Caterina Bendotti, Jochen H. M. Prehn, Giovanni Nardo   +13 more
wiley   +1 more source

AN IMPROVED MICROBIOLOGICAL METHOD FOR THE DETERMINATION OF NICOTINIC ACID BASED ON THE USE OF PROTEUS HX19

, 1947
N. Grossowicz, E. Sherstinsky
openalex   +1 more source

Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B

Proceedings of the National Academy of Sciences of the United States of America, 2009
Y. Irukayama-tomobe, Hirokazu Tanaka, T. Yokomizo, Tomomi Hashidate-Yoshida, M. Yanagisawa, T. Sakurai   +5 more
semanticscholar   +1 more source

High Concentrations of Circulating 2PY and 4PY-Potential Risk Factor of Cardiovascular Disease in Patients with Chronic Kidney Disease. [PDF]

Int J Mol Sci
Dettlaff-Pokora A, Swierczynski J.
europepmc   +1 more source

G protein‐coupled receptor‐mediated autophagy in health and disease

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan, Zeynep Aslıhan Durer, Beki Kan   +2 more
wiley   +1 more source

Oral nicotinic acid administration effect on lipids, thyroid hormones, and oxidative stress in intact adult dogs. [PDF]

BMC Vet Res
Derakhshandeh N, Nazifi S, Mogheiseh A, Divar MR, Dadvand Z, Karimizadeh MS, Zeidabadi M.   +6 more
europepmc   +1 more source

Microbial Degradation of Nicotine and Nicotinic Acid

, 1955
Takeshi Tabuchi
openalex   +2 more sources

The Requirements of Poultry for Aneurin, Choline, Folic Acid, Nicotinic Acid, Pantothenic Acid and Riboflavin [PDF]

, 1949
J. Duckworth, G. M. Ellinge
openalex   +1 more source