Results 221 to 230 of about 34,315 (270)

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu   +6 more
wiley   +1 more source

Hepatic FGF21 Deletion Improves Glucose Metabolism, Alters Lipogenic and <i>Chrna4</i> Gene Expression, and Enhances Telomere Maintenance in Aged Female Mice. [PDF]

open access: yesInt J Mol Sci
Torres-Oteros D   +7 more
europepmc   +1 more source

Comparative lipidomic and proteomic analysis reveals species‐specific differences in midgut composition and insecticide absorption between Apis mellifera and Bombus terrestris

open access: yesPest Management Science, Volume 82, Issue 2, Page 1540-1551, February 2026.
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas   +7 more
wiley   +1 more source

Comparative multi‐omics in female mice reveals tissue‐specific vulnerabilities to chronic alcohol intake

open access: yesAlcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis   +6 more
wiley   +1 more source

Ribosomal Synthesis of Topologically Defined Thioisoindole‐Bridged Bicyclic Peptides

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
A flexible in vitro translation (FIT) system‐based strategy for ribosomal synthesis of thioisoindole‐bridged bicyclic (TiB) peptides is developed. The flexizyme substrate Ac‐Ala(NtBA)Sc‐CME is efficiently incorporated into FIT to generate ribosomal peptides bearing N‐terminal Ac‐Ala(NtBA)Sc as the cyclization handle, which after mild deprotection ...
Yue Zhang   +3 more
wiley   +2 more sources

Insights into host dependency from a chemically defined medium for the human vaginal bacterium Lactobacillus crispatus. [PDF]

open access: yesArch Microbiol
Achterberg P   +5 more
europepmc   +1 more source

Endocrine Functions of Bone Are Suppressed by Orally Administered Glucose Regardless of Bodyweight

open access: yesClinical Endocrinology, Volume 104, Issue 2, Page 130-138, February 2026.
ABSTRACT Objective Bone is a target for diabetic complications, but the impact of metabolic changes on bone metabolism is less understood. Bones participate in energy metabolism by via secreted osteokines. Glucose ingestion reduces bone resorption, but the effects on osteokines remain unknown. Further, it is not known whether the response is altered in
Niki Jalava   +4 more
wiley   +1 more source

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