Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu +6 more
wiley +1 more source
Hepatic FGF21 Deletion Improves Glucose Metabolism, Alters Lipogenic and <i>Chrna4</i> Gene Expression, and Enhances Telomere Maintenance in Aged Female Mice. [PDF]
Torres-Oteros D +7 more
europepmc +1 more source
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas +7 more
wiley +1 more source
Simultaneous quantification of 12 water-soluble vitamins in MDCK cell culture media by eco-friendly ion-pairing reagent-free HPLC-UV. [PDF]
Zhou L, Zhang M, Sun H, Duan L, Meng Q.
europepmc +1 more source
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis +6 more
wiley +1 more source
Ribosomal Synthesis of Topologically Defined Thioisoindole‐Bridged Bicyclic Peptides
A flexible in vitro translation (FIT) system‐based strategy for ribosomal synthesis of thioisoindole‐bridged bicyclic (TiB) peptides is developed. The flexizyme substrate Ac‐Ala(NtBA)Sc‐CME is efficiently incorporated into FIT to generate ribosomal peptides bearing N‐terminal Ac‐Ala(NtBA)Sc as the cyclization handle, which after mild deprotection ...
Yue Zhang +3 more
wiley +2 more sources
Insights into host dependency from a chemically defined medium for the human vaginal bacterium Lactobacillus crispatus. [PDF]
Achterberg P +5 more
europepmc +1 more source
Endocrine Functions of Bone Are Suppressed by Orally Administered Glucose Regardless of Bodyweight
ABSTRACT Objective Bone is a target for diabetic complications, but the impact of metabolic changes on bone metabolism is less understood. Bones participate in energy metabolism by via secreted osteokines. Glucose ingestion reduces bone resorption, but the effects on osteokines remain unknown. Further, it is not known whether the response is altered in
Niki Jalava +4 more
wiley +1 more source
The Roles of Moonlighting Nicotinamide Mononucleotide Adenylyl Transferases in Cell Physiology. [PDF]
Lee YC, Lin SJ.
europepmc +1 more source

