Results 261 to 270 of about 65,529 (332)

The Effect of Clay‐ and Yeast‐Based Mycotoxin Binder on Performance, Lymphoid Organs, Blood Parameters, Immune Response and Haematology Parameters of Broilers Exposed to Aflatoxin B1

Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.
Broilers fed diets contaminated with 200 µg/kg AFB1 showed poor growth performance throughout the period. These adverse effects of aflatoxicosis may be associated with liver dysfunction, immune dysfunction and inflammation of immune organs. However, supplementation of 1 g/kg MAG counteracted the negative effects caused by AFB1, reducing liver ...
Payman Mahmoudi Nasr, Kaveh Jafari Khorshidi   +1 more
wiley   +1 more source

Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model. [PDF]

Sci Rep
Lassota A, Hodge JJL, Soller M.
europepmc   +1 more source

On the Mechanism of Action of Nicotinic Acid in Lowering Serum Lipids

, 1962
O. Neal Miller, James G. Hamilton, Grace A. Goldsmith   +2 more
openalex   +1 more source

Electrochemical Point‐of‐Care Test for Assessing Serum Paracetamol Concentration: Comparison With Traditional Methods and Detection of Concomitant Drugs

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
ABSTRACT Rapid serum paracetamol (acetaminophen) concentration measurement is essential in suspected intoxication, but centralized laboratory analyses often delay initiation of antidotal therapy. We studied the feasibility of a novel electrochemical single‐walled carbon nanotube/Nafion‐based point‐of‐care (POC) method in detecting paracetamol in 99 ...
Johanna K. Kujala, Terhi J. Lohela, Niklas Wester, Elsi Verrinder, Anna Pelander, Tea Lamberg, Björn Mikladal, Eija A. Kalso, Tuomas O. Lilius   +8 more
wiley   +1 more source

Dual-omics analysis reveals B vitamin regulation and metabolism in Areca Catechu inflorescence. [PDF]

BMC Genomics
Jiang W, Liu X, Li W, Yang J, Li P, Xie M, Zhou G.   +6 more
europepmc   +1 more source

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, Volume 182, Issue 21, Page 5090-5118, November 2025.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

Targeted metabolomic evaluation of peripheral blood mononucleated cells from patients with PMM2-CDG. [PDF]

Sci Rep
Mangione R, Cirnigliaro L, Saab MW, Pettinato F, Barbato A, Distefano A, Spina E, Lazzarino G, Volti GL, Longhitano L, Tibullo D, Pittalà A, Giallongo C, Di Pietro V, Tabbi G, Longo SA, Graziani A, Tavazzi B, Amorini AM, Lazzarino G, Barone R.   +20 more
europepmc   +1 more source

Structure–activity relationship of the allosteric effects of ivermectin at human P2X4 and GABAA receptors

British Journal of Pharmacology, Volume 182, Issue 21, Page 5286-5302, November 2025.
Abstract Background and purpose Positive allosteric modulation of the P2X4 receptor is a potential route to providing cardiovascular benefit through enhancing flow‐dependent arterial vasodilation and providing cardioprotection. However, ligands that selectively enhance P2X4 activity are absent.
Jessica L. Meades, Marcella Bassetto, Marius C. Staiculescu, Gayathri Swaminath, Samuel J. Fountain   +4 more
wiley   +1 more source

High Concentrations of Circulating 2PY and 4PY-Potential Risk Factor of Cardiovascular Disease in Patients with Chronic Kidney Disease. [PDF]

Int J Mol Sci
Dettlaff-Pokora A, Swierczynski J.
europepmc   +1 more source

Digitally enhanced ketogenic diet versus low‐fat diet for cardio‐renal‐metabolic health in a predominantly Hispanic adult population with overweight or obesity: Pilot randomised clinical trial

Diabetes, Obesity and Metabolism, Volume 27, Issue 11, Page 6154-6166, November 2025.
Abstract Aims Individuals respond differently to diets for weight loss and cardio–renal–metabolic health. Advances in digital health and metabolomics hold promise for personalised lifestyle interventions. The study evaluated the feasibility and the preliminary efficacy of a digitally enhanced ketogenic diet compared with a low‐fat diet, and explored ...
Yan Du, Jing Wang, Shiyu Li, Christiane Meireles, Afaf Saliba, Alondra Castillo, Martin Goros, Johnathan Gelfond, Byeong Yeob Choi, Lu Qi, Chengdong Li, Kumar Sharma   +11 more
wiley   +1 more source