Results 231 to 240 of about 493,465 (339)

The ATP-mediated cytokine release by macrophages is down-modulated by unconventional α9* nicotinic acetylcholine receptors. [PDF]

Front Immunol
Wolf PMK, Hanke D, Singh VK, Keller HL, Ettischer LJ, Teppe L, Amati AL, Hecker A, Husain-Syed F, Rohde M, Nuber UA, Büttner K, McIntosh JM, Liese J, Mazurek S, Grau V, Richter K.   +16 more
europepmc   +1 more source

Expeditious Synthesis, Enantiomeric Resolution, and Enantiomer Functional Characterization of (4-(4-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): An Allosteric Agonist-Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors

, 2013
Ganesh A. Thakur, Abhijit Kulkarni, Jeffrey R. Deschamps, Roger L. Papke   +3 more
openalex   +1 more source

GLP‐1RA and Liver Fibrosis Progression in MASLD and Type 2 Diabetes: Target Trial Emulation Using Propensity Score Matching

Liver International, Volume 45, Issue 12, December 2025.
ABSTRACT Background and Aims GLP‐1 receptor agonists (GLP‐1RA) are widely used in type 2 diabetes mellitus (T2DM) and may confer hepatoprotective effects in metabolic dysfunction‐associated steatotic liver disease (MASLD). Their impact on liver fibrosis progression in real‐world clinical settings remains unclear.
Jonggi Choi, Tushar Kamath, Vy H. Nguyen, Eric Przybyszewski, Jiunn Song, Allison Carroll, Megan Michta, Erik Almazan, Tracey G. Simon, Raymond T. Chung   +9 more
wiley   +1 more source

Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates – subtype selective, high affinity α7 nicotinic acetylcholine receptor agonists

, 2009
Christopher J. O’Donnell, Langu Peng, Brian T. O’Neill, Eric P. Arnold, Robert J. Mather, Steven B. Sands, Alka Shrikhande, Lorraine A. Lebel, Douglas K. Spracklin, Frank M. Nedza   +9 more
openalex   +1 more source

Effects of Nicotinic Acetylcholine Receptor Agonists in Assays of Acute Pain-Stimulated and Pain-Depressed Behaviors in Rats [PDF]

, 2015
Kelen Freitas, F. Ivy Carroll, S. Stevens Negus   +2 more
openalex   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

Nicotinic α7 and α4β2 agonists enhance the formation and retrieval of recognition memory: Potential mechanisms for cognitive performance enhancement in neurological and psychiatric disorders

, 2015
Samantha L. McLean, Ben Grayson, Samuel Marsh, Samah H. O. Zarroug, Michael Harte, Joanna C. Neill   +5 more
openalex   +2 more sources

Antiamnesic activity of the nicotinic agonist DBO-83 in mice [PDF]

, 1998
Carla Ghelardini, Nicoletta Galeotti, Francesco Giuliani, Daniela Barlocco, Alessandro Bartolini   +4 more
openalex   +1 more source

Microvascular arteriolar reactivity in response to skeletal muscle contractions in female and male hamsters

Physiological Reports, Volume 13, Issue 23, December 2025.
Abstract Microvascular control mechanisms involved in the blood flow response to muscle contractions have been well documented in males but remain poorly understood in females. Therefore, we characterized arteriolar vasodilation in situ using intravital microscopy of the retractor muscle of anesthetized female and male hamsters (8–13 weeks). Arterioles
Nicole M. Fletcher, Coral L. Murrant
wiley   +1 more source

Selective α7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis [PDF]

, 2010
Susanne A. Snoek, Marleen I. Verstege, Esmerij P. van der Zanden, Nigel Deeks, David C. Bulmer, Michael J. Skynner, Kevin Lee, Anje A. te Velde, Guy E. Boeckxstaens, Wouter J. de Jonge   +9 more
openalex   +1 more source