The role of acetylcholine and its receptors in tumor immune regulation: mechanisms and potential therapeutic targets. [PDF]
Zhang C, Guo X, Wang Y, Zhang S, Wang Z.
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The Functional Topology of Phenylpiperazinium Agonists and Antagonists on the Nicotinic Acetylcholine Receptor Landscape: Pointing the Way for Future Therapeutic Management of Inflammation and Neuropathic Pain. [PDF]
Andleeb H, Gulsevin A, Papke RL.
europepmc +1 more source
Development of a Novel Method to Quantify Quinolinic Acid in Biological Samples. [PDF]
Tasaka M +8 more
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Nicotinic Signaling Stimulates Glucagon Secretion in Mouse and Human Pancreatic α-Cells. [PDF]
Hamilton A +9 more
europepmc +1 more source
Nociceptor α7nAChR activation blunts neuronal HMGB1 release and attenuates inflammation and nociceptive behavior. [PDF]
Yang H +10 more
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How Varenicline Works: Identifying Critical Receptor and Ligand-based Interactions
Aiken SG +14 more
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Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist
Psychopharmacology, 1995ABT-418, a novel cholinergic ligand, was reported to possess potent cognitive-enhancing and anxiolytic properties in animal models with reduced side effects (Decker et al. 1994; Garvey et al. 1994) suggesting selectivity of effects. In this study, the binding properties of ABT-418 to [3H]-nicotine sites were evaluated and its pharmacology investigated ...
M. Damaj +5 more
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Nicotinic Agonists and Psychosis
Current Drug Target -CNS & Neurological Disorders, 2002Schizophrenia patients have insufficient inhibitory processing of identical paired auditory stimuli. This deficient "auditory gating" is thought to have physiological relevance, and its severity correlates with certain measures of both positive and negative symptoms.
J K, Simosky, K E, Stevens, R, Freedman
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Effects of nicotinic agonists on the NMDA receptor
Brain Research, 1991The cholinergic nicotinic agonists (-)nicotine and lobeline were observed to partially inhibit whole-cell N-methyl-D-aspartate (NMDA)-induced responses in rat cortical neurons in culture. In addition we found that (-)nicotine, (+)nicotine, and lobeline, but not the nicotine metabolite (-)cotinine nor acetylcholine, were able to displace [3H]dizocilpine
E, Aizenman, L H, Tang, I J, Reynolds
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