Results 41 to 50 of about 41,031 (306)

Equilibrium Properties of Mouse-Torpedo Acetylcholine Receptor Hybrids Expressed in Xenopus Oocytes [PDF]

open access: yes, 1987
This study used messenger RNA encoding each subunit (α, β, γ and δ) of the nicotinic acetylcholine (ACh) receptor from mouse BC3H-1 cells and from Torpedo electric organ.
Davidson, Norman   +4 more
core   +3 more sources

C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation

open access: yesFrontiers in Immunology, 2018
Blood levels of the acute phase reactant C-reactive protein (CRP) are frequently measured as a clinical marker for inflammation, but the biological functions of CRP are still controversial.
Katrin Richter   +22 more
doaj   +1 more source

Activation of muscle nicotinic acetylcholine receptor channels by nicotinic and muscarinic agonists [PDF]

open access: yesBritish Journal of Pharmacology, 1999
The dose‐response parameters of recombinant mouse adult neuromuscular acetylcholine receptor channels (nAChR) activated by carbamylcholine, nicotine, muscarine and oxotremorine were measured. Rate constants for agonist association and dissociation, and channel opening and closing, were estimated from single‐channel kinetic analysis.
Gustav Akk, Anthony Auerbach
openaire   +3 more sources

An expanding range of targets for kynurenine metabolites of tryptophan [PDF]

open access: yes, 2013
The kynurenine pathway of tryptophan metabolism accounts for most of the tryptophan that is not committed to protein synthesis and includes compounds active in the nervous and immune systems.
Darlington, L. Gail   +2 more
core   +1 more source

Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior [PDF]

open access: yes, 2003
Prenatal nicotine exposure has been linked to attention deficit hyperactivity disorder and cognitive impairment, but the sites of action for these effects of nicotine are still under investigation. High-affinity nicotinic acetylcholine receptors (nAChRs)
Caldarone, Barbara J   +7 more
core   +2 more sources

Medial Septum Modulates Cellular Response Induced in Hippocampus on Microinjection of Cholinergic Agonists into Hypothalamic Lateral Supramammillary Nucleus

open access: yesFrontiers in Neuroanatomy, 2017
Cholinergic mechanisms in supramammillary nucleus (SuM), especially the lateral SuM (lSuM) modulates septo-hippocampal neural activity. The lSuM, as compared to the contiguous medial SuM (mSuM) has relatively dense projections to hippocampus and ...
Mohammed Z. Ariffin   +4 more
doaj   +1 more source

1,2,3,4-Tetrahydro-1,4-methanonaphthalene-2,3-diol

open access: yesActa Crystallographica Section E, 2009
The title compound, C11H12O2, is an intermediate in the synthesis of Varenicline, a nicotinic receptor partial agonist used to treat smoking addiction. In the crystal structure, there is an intramolecular O—H...O hydrogen bond that generates an S(5)
Jian Xu   +4 more
doaj   +1 more source

Cholinergic modulation of dopamine overflow in the rat neostriatum: A fast cyclic voltammetric study in vitro [PDF]

open access: yes, 1994
Stimulus-evoked dopamine overflow in rat neostriatal slices was determined using fast cyclic voltammetry. The dopamine efflux induced by intrastriatal stimulation increased with stimulus intensity and was found to be enhanced by more than 100% upon ...
Kudernatsch, Martina, Sutor, Bernd
core   +1 more source

Evaluation of the cholinomimetic actions of trimethylsulfonium, a compound present in the midgut gland of the sea hare Aplysia brasiliana (Gastropoda, Opisthobranchia)

open access: yesBrazilian Journal of Medical and Biological Research, 2002
Trimethylsulfonium, a compound present in the midgut gland of the sea hare Aplysia brasiliana, negatively modulates vagal response, indicating a probable ability to inhibit cholinergic responses.
C.M. Kerchove   +3 more
doaj   +1 more source

Suppression of methamphetamine-seeking behavior by nicotinic agonists [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
To understand the mechanism of methamphetamine (MAP) craving from the viewpoint of nicotinic acetylcholinergic transmission, we examined the responsible site of the brain for anticraving effects produced by nicotinic agonists by using a MAP self-administration paradigm in rats.
Katsuya Sakimura   +4 more
openaire   +3 more sources

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